ID I2F4B8_9BACT Unreviewed; 439 AA.
AC I2F4B8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Cell wall-associated hydrolase, invasion-associated protein {ECO:0000313|EMBL:AFK06771.1};
GN ORFNames=Theba_1066 {ECO:0000313|EMBL:AFK06771.1};
OS Mesotoga prima MesG1.Ag.4.2.
OC Bacteria; Thermotogota; Thermotogae; Kosmotogales; Kosmotogaceae; Mesotoga.
OX NCBI_TaxID=660470 {ECO:0000313|EMBL:AFK06771.1, ECO:0000313|Proteomes:UP000002881};
RN [1] {ECO:0000313|EMBL:AFK06771.1, ECO:0000313|Proteomes:UP000002881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mesG1.Ag.4.2 {ECO:0000313|Proteomes:UP000002881};
RX PubMed=22798451;
RA Zhaxybayeva O., Swithers K.S., Foght J., Green A.G., Bruce D., Detter C.,
RA Han S., Teshima H., Han J., Woyke T., Pitluck S., Nolan M., Ivanova N.,
RA Pati A., Land M.L., Dlutek M., Doolittle W.F., Noll K.M., Nesbo C.L.;
RT "Genome Sequence of the Mesophilic Thermotogales Bacterium Mesotoga prima
RT MesG1.Ag.4.2 Reveals the Largest Thermotogales Genome To Date.";
RL Genome Biol. Evol. 4:700-708(2012).
CC -!- SIMILARITY: Belongs to the peptidase C40 family.
CC {ECO:0000256|ARBA:ARBA00007074}.
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DR EMBL; CP003532; AFK06771.1; -; Genomic_DNA.
DR RefSeq; WP_014730769.1; NC_017934.1.
DR AlphaFoldDB; I2F4B8; -.
DR STRING; 660470.Theba_1066; -.
DR KEGG; mpg:Theba_1066; -.
DR eggNOG; COG0791; Bacteria.
DR HOGENOM; CLU_045651_0_0_0; -.
DR Proteomes; UP000002881; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR InterPro; IPR000064; NLP_P60_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR039439; SH3b1_dom.
DR Pfam; PF00877; NLPC_P60; 1.
DR Pfam; PF12913; SH3_6; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:AFK06771.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002881}.
FT DOMAIN 146..185
FT /note="SH3b1"
FT /evidence="ECO:0000259|Pfam:PF12913"
FT DOMAIN 304..384
FT /note="NlpC/P60"
FT /evidence="ECO:0000259|Pfam:PF00877"
SQ SEQUENCE 439 AA; 49566 MW; 261B2F9E4A3A7710 CRC64;
MEKYIATPEG VLPEKQESDY WCRRMENPDA VWMLKDEIES FNSAIILRAR EAGKLEFACS
LEDCPSSVPF EEVRRSINDT IPETFFQRSL LTSEGDKVPA EIRNDIIDNA TAILNQDMAV
RFGLVTQRTN LRVLPTDLIS CDEYIDNDML QLTAVSIGTP FALLARSRDM SWLFVQTPFY
RGWIKANDTA TAKKRGAVMS FMKASPFLLA TGNRVEIEPD PFAINSLGLI LQMGDRLPLE
KPTENENLHA QGPFSCFTVS VPYRDRLGLL GFRKALVRMS EDVRIGDLDL TGRAILDQAF
KMLGERYGWG DLYNRRDCSR FVRDIYASFG IFLPRDAWAQ ERFGSSNKVV FEGDAEHRKS
QLSSLRPGNP LYMPGHTLIY LGEENGSFFA IHDGAGYRDS KGKKVSVHGV FVVDLSVRTM
NSDKSYLEQL TTALRIDSA
//
