ID I2F5H7_9BACT Unreviewed; 512 AA.
AC I2F5H7;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Acetyl-CoA carboxylase, carboxyltransferase component (Subunits alpha and beta) {ECO:0000313|EMBL:AFK07180.1};
GN ORFNames=Theba_1498 {ECO:0000313|EMBL:AFK07180.1};
OS Mesotoga prima MesG1.Ag.4.2.
OC Bacteria; Thermotogota; Thermotogae; Kosmotogales; Kosmotogaceae; Mesotoga.
OX NCBI_TaxID=660470 {ECO:0000313|EMBL:AFK07180.1, ECO:0000313|Proteomes:UP000002881};
RN [1] {ECO:0000313|EMBL:AFK07180.1, ECO:0000313|Proteomes:UP000002881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mesG1.Ag.4.2 {ECO:0000313|Proteomes:UP000002881};
RX PubMed=22798451;
RA Zhaxybayeva O., Swithers K.S., Foght J., Green A.G., Bruce D., Detter C.,
RA Han S., Teshima H., Han J., Woyke T., Pitluck S., Nolan M., Ivanova N.,
RA Pati A., Land M.L., Dlutek M., Doolittle W.F., Noll K.M., Nesbo C.L.;
RT "Genome Sequence of the Mesophilic Thermotogales Bacterium Mesotoga prima
RT MesG1.Ag.4.2 Reveals the Largest Thermotogales Genome To Date.";
RL Genome Biol. Evol. 4:700-708(2012).
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DR EMBL; CP003532; AFK07180.1; -; Genomic_DNA.
DR RefSeq; WP_014731108.1; NC_017934.1.
DR AlphaFoldDB; I2F5H7; -.
DR STRING; 660470.Theba_1498; -.
DR KEGG; mpg:Theba_1498; -.
DR eggNOG; COG4799; Bacteria.
DR HOGENOM; CLU_018822_6_2_0; -.
DR Proteomes; UP000002881; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR InterPro; IPR034733; AcCoA_carboxyl_beta.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011763; COA_CT_C.
DR InterPro; IPR011762; COA_CT_N.
DR PANTHER; PTHR43842:SF2; BIOTIN-DEPENDENT ACETYL-_PROPIONYL-COENZYME A CARBOXYLASE BETA5 SUBUNIT; 1.
DR PANTHER; PTHR43842; PROPIONYL-COA CARBOXYLASE BETA CHAIN; 1.
DR Pfam; PF01039; Carboxyl_trans; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
DR PROSITE; PS50989; COA_CT_CTER; 1.
DR PROSITE; PS50980; COA_CT_NTER; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002881};
KW Transferase {ECO:0000313|EMBL:AFK07180.1}.
FT DOMAIN 1..257
FT /note="CoA carboxyltransferase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50980"
FT DOMAIN 259..494
FT /note="CoA carboxyltransferase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50989"
SQ SEQUENCE 512 AA; 55675 MW; 16ACA653B0806B54 CRC64;
MTGRLEEFFE KSEKITLGGG QDKIEKHHKS GKLTARERID ALCDEGSFEE FDRFVKHRAT
SFGLENKEFP ADGVITGIGT VNGRKIAVFS QDFTVQGGSL GEMHAKKIMK VQDMAMKLGI
PIVGINDSGG ARIQEGVDSL FGYGGIFHRN TLSSGVIPQI TVICGPCAGG AVYSPAITDF
IVMTDKHSQM FITGPQVIKA VTGEETSMEE LGGALVHNTK SGNAHFLVPD DKNAMLLVRE
LLEYLPQNNS EEPLKTESTV SDPVLELREI VPDNPKQSYD IKKVISLVVD DGKFLEVHEH
YAKNMVIGFA RIGGRSVGIV ANQPSVFAGS LDINASDKAA RFIRFLDAFN LPIITFVDTP
GFLPGISQEH GGIIRHGAKL LYSYSEASVQ KITLILRKAY GGAYIAMGSQ HLGADIVFAW
PGAEIAVMGP EGAANIIFKR EIDASGNPEK TRQEKIAEYK DVFANPFVAA GRGYIESIID
PAESRREIIR ALETLDTKVE GRPSKKHGNI PL
//
