ID I2F8I7_9BACT Unreviewed; 354 AA.
AC I2F8I7;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Transport permease protein {ECO:0000256|RuleBase:RU361157};
GN ORFNames=Theba_2640 {ECO:0000313|EMBL:AFK08240.1};
OS Mesotoga prima MesG1.Ag.4.2.
OC Bacteria; Thermotogota; Thermotogae; Kosmotogales; Kosmotogaceae; Mesotoga.
OX NCBI_TaxID=660470 {ECO:0000313|EMBL:AFK08240.1, ECO:0000313|Proteomes:UP000002881};
RN [1] {ECO:0000313|EMBL:AFK08240.1, ECO:0000313|Proteomes:UP000002881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mesG1.Ag.4.2 {ECO:0000313|Proteomes:UP000002881};
RX PubMed=22798451;
RA Zhaxybayeva O., Swithers K.S., Foght J., Green A.G., Bruce D., Detter C.,
RA Han S., Teshima H., Han J., Woyke T., Pitluck S., Nolan M., Ivanova N.,
RA Pati A., Land M.L., Dlutek M., Doolittle W.F., Noll K.M., Nesbo C.L.;
RT "Genome Sequence of the Mesophilic Thermotogales Bacterium Mesotoga prima
RT MesG1.Ag.4.2 Reveals the Largest Thermotogales Genome To Date.";
RL Genome Biol. Evol. 4:700-708(2012).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU361157};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU361157}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC-2 integral membrane protein family.
CC {ECO:0000256|RuleBase:RU361157}.
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DR EMBL; CP003532; AFK08240.1; -; Genomic_DNA.
DR RefSeq; WP_006487237.1; NC_017934.1.
DR AlphaFoldDB; I2F8I7; -.
DR STRING; 660470.Theba_2640; -.
DR KEGG; mpg:Theba_2640; -.
DR eggNOG; COG0842; Bacteria.
DR HOGENOM; CLU_039483_0_0_0; -.
DR Proteomes; UP000002881; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR047817; ABC2_TM_bact-type.
DR InterPro; IPR000412; ABC_2_transport.
DR PANTHER; PTHR43027; DOXORUBICIN RESISTANCE ABC TRANSPORTER PERMEASE PROTEIN DRRC-RELATED; 1.
DR PANTHER; PTHR43027:SF1; DOXORUBICIN RESISTANCE ABC TRANSPORTER PERMEASE PROTEIN DRRC-RELATED; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR PRINTS; PR00164; ABC2TRNSPORT.
DR PROSITE; PS51012; ABC_TM2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU361157};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361157};
KW Reference proteome {ECO:0000313|Proteomes:UP000002881};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361157};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361157}; Transport {ECO:0000256|RuleBase:RU361157}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 160..183
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 204..227
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 239..264
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 276..294
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT DOMAIN 123..354
FT /note="ABC transmembrane type-2"
FT /evidence="ECO:0000259|PROSITE:PS51012"
SQ SEQUENCE 354 AA; 39673 MW; CCE56DFED4775082 CRC64;
MSRNSLKPVF IAFAKEAFRN RLEIFFTLFF PMIFLLLFGF FFGGSESYQK VSVGLYQTGP
YDISAVIEES GAWNLRLYDG ETDIGEAVKN GDILLGMIFN GEKITYLHQE GNLEQQSTIE
MARASISAAV EKKINNARSF IVVENIPETA GRIRATDADY TMSGVIAISL LSAGMFSVIS
VFGRYRKRGV LDRFKITPLR PFTFVLGSTL TRFLVSLVSI VLILVVSRLL FRTTFQIDWL
PFLVSILSST LGMMALGLFL TLLFRNPETA DTAASILMVI MVFLAGIYFP LSFLPDYLRV
ISMFLPVKYV AELIRHSLGI EFVSTSYFVI TNLVLFLSGV VLLYFTGKRY LSAS
//
