ID I2GRZ8_9BACT Unreviewed; 655 AA.
AC I2GRZ8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=ATP-dependent DNA helicase, RecQ family {ECO:0000313|EMBL:CCH56676.1};
GN ORFNames=BN8_06057 {ECO:0000313|EMBL:CCH56676.1};
OS Fibrisoma limi BUZ 3.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Fibrisoma.
OX NCBI_TaxID=1185876 {ECO:0000313|EMBL:CCH56676.1, ECO:0000313|Proteomes:UP000009309};
RN [1] {ECO:0000313|EMBL:CCH56676.1, ECO:0000313|Proteomes:UP000009309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BUZ 3T {ECO:0000313|Proteomes:UP000009309};
RX PubMed=22843583; DOI=10.1128/jb.00869-12;
RA Filippini M., Qi W., Jaenicke S., Goesmann A., Smits T.H., Bagheri H.C.;
RT "Genome Sequence of the Filamentous Bacterium Fibrisoma limi BUZ 3T.";
RL J. Bacteriol. 194:4445-4445(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH56676.1}.
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DR EMBL; CAIT01000009; CCH56676.1; -; Genomic_DNA.
DR AlphaFoldDB; I2GRZ8; -.
DR STRING; 1185876.BN8_06057; -.
DR eggNOG; COG0514; Bacteria.
DR Proteomes; UP000009309; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CCH56676.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000009309}.
FT DOMAIN 43..211
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 235..378
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 655 AA; 74506 MW; 52F96C6D5C03C9F6 CRC64;
MYNDNWSELS DLGCIFAVSM TVRQILQQFW GYSSFRPMQE DVVDAVLARQ DTLVLMPTGG
GKSICFQVPA LAMKGICIVV TPLIALMKDQ VEQLRRRGIP AAAIYSGMHY REIDAILDNC
IYGNTKFLYV SPERLRTELV IERVKQMMVC LLAVDEAHCI SAWGYDFRPP YLQIAEFREL
IPETPIVALT ASATPEVQTD IVDKLALREP TVFRQTFARP NLSYSVIQEE NKENRLLRVL
TNVPGCAVVY VRSRRQTQQV ASWLTRHGIS ADFYHAGLTT QQRGDKQDAW IHDRMRVMVA
TNAFGMGIDK PDVRVVVHLD VPDTLEAYYQ EAGRAGRDGQ KAYAVLLYNQ GDLSGLQYKT
EQLYPPVDLL RRVYQALANY TAVPVGGGEF NSYDFDLQTF TTNFKLPAQE THYALKQLQL
EGFIELSETY FHPSRLSMTL DNRELYEFQV MNPRFDPFLK LVLRMYGGEL FTDFVTISES
ALARAFLVDQ KEIVTLLEQL HQRNVVVYEK QKDKPQLVFL TPRFDAPQLP VNVPELNERK
QRALRKVQAA TTYVEHPTQC RTRLLQAYFG EKPADPCGIC DNCLKQKKKA GSVLGEVREQ
VRQYVALANG PGVSPRQLSY HFAQTDADTL AETIRLMLAE EEIKYNKAGN LTLNA
//
