ID I2H0C0_TETBL Unreviewed; 2358 AA.
AC I2H0C0;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=GIT Spa2 homology (SHD) domain-containing protein {ECO:0000259|SMART:SM00555};
GN Name=TBLA0B10050 {ECO:0000313|EMBL:CCH59822.1};
GN ORFNames=TBLA_0B10050 {ECO:0000313|EMBL:CCH59822.1};
OS Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC
OS 10599 / NRRL Y-10934 / UCD 77-7) (Yeast) (Kluyveromyces blattae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX NCBI_TaxID=1071380 {ECO:0000313|EMBL:CCH59822.1, ECO:0000313|Proteomes:UP000002866};
RN [1] {ECO:0000313|EMBL:CCH59822.1, ECO:0000313|Proteomes:UP000002866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 /
RC UCD 77-7 {ECO:0000313|Proteomes:UP000002866};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
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DR EMBL; HE806317; CCH59822.1; -; Genomic_DNA.
DR RefSeq; XP_004179341.1; XM_004179293.1.
DR STRING; 1071380.I2H0C0; -.
DR GeneID; 14494258; -.
DR KEGG; tbl:TBLA_0B10050; -.
DR eggNOG; ENOG502QS1N; Eukaryota.
DR HOGENOM; CLU_002012_0_0_1; -.
DR InParanoid; I2H0C0; -.
DR OMA; SISMNQS; -.
DR OrthoDB; 1384359at2759; -.
DR Proteomes; UP000002866; Chromosome 2.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 1.
DR InterPro; IPR022018; GIT1_C.
DR InterPro; IPR013724; GIT_SHD.
DR InterPro; IPR039892; Spa2/Sph1.
DR PANTHER; PTHR21601:SF0; PROTEIN SPA2-RELATED; 1.
DR PANTHER; PTHR21601; SPA2 PROTEIN; 1.
DR Pfam; PF12205; GIT1_C; 1.
DR Pfam; PF08518; GIT_SHD; 2.
DR SMART; SM00555; GIT; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002866};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 44..74
FT /note="GIT Spa2 homology (SHD)"
FT /evidence="ECO:0000259|SMART:SM00555"
FT DOMAIN 94..124
FT /note="GIT Spa2 homology (SHD)"
FT /evidence="ECO:0000259|SMART:SM00555"
FT REGION 171..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 474..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 603..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 833..870
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 918..1068
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1238..1270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1286..1332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1695..1726
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1751..1775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1804..1842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2097..2196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 630..664
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 171..233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 528..543
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 918..1012
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1013..1029
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1030..1068
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2111..2141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2150..2188
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2358 AA; 261723 MW; E395D29BE112F258 CRC64;
MSSSTEFSKA QQRDMFSYYQ ALQTFSDVIG LNNAQTTSSR AQKARGKLLK LSAAQFYELG
TDVYDELKRR IDEDQNQPEY LLPKATFHMK RNQARQKLAN LSQSRFGDLV NDILYEITRR
GYNSDPDIPD THQKNISLSS SIINNTSSND PINLNTSTNN KNAQHSNIEI PNTHINNSDL
NKNNNTNNPS KILSPIDARP STSIGDGTPS PVTSLPHSSI QPSKVIPQKA SIDWSSSEDE
DDSENNTDTN IDTNTNTNTN TNNTNTNTNT NNTKDLIINS IPNNSPIATT SPIESTISTT
PNNHLNENTI TNDNLKNSTM KNSIQNNLGN NASVNIKSDI NDKPQLDTIS NNSFGDNLND
TPDLNDFNST PLLNDMSNKL ELSSPATNFS EKEMSPVLPL KPHHDAPTPN TKLADLDKEL
QKYNLNTNNN PILDLDGNSD EIVTDADTRN INNYSNNIIP VEPKLISEND NKADTYHNAS
RSSPSNQTNF DDTNMNNDSA DDDSKTDIIQ KIKEPAYEYV SNNVIGYREG RNSEDNTPII
PSKDTPSDRY IETPIATRAS LNIDEDEYNS LKDKYSQLNL KNMQLQEELA NMKNLFQSAQ
QLKQSNETND DSMQPQRAPS SESSTVLSLN ENFKNEMMSM STQLSDLSIE NETLRQHISE
LELQLRKNTA SERSINKQIT EQDGTKSLLM NFHSENKSLT QDMVKAHISS NGLITLQQLQ
AFHSIIFTLY QETDLKSKEM GSNLFKALSS LSNIIKRVLD ESLSQESNDQ AILLRASFSH
LITSIRYFCV YDDVLPNITV NAAIADVIFA FCNLVNKVKL RLTNELPTIT TSTVSTEIPK
SNDLSSHSIE KPTANDSYES LSQSSLDIPK PTLIDNSEDG HMEMSPVKPL KLTQKINSSQ
QIQPQSARKI SGTNLFSSMF NSRTTSNNKE GSESGNFNPQ TPINRKIRAT SSHNSSSVSI
GSDEPNLSVA LSSNRSLSTP TGSAPELQNK ITDNSKITTN IATSSNLSEK NLDRNVSPEE
GKTPERNNKR ADFNSISTST PAIDRKQDVN DPNSISSPTT SNSPKDVLNI NNESIITTAK
DNDSQTHMAL QSEEQKIYSS VNKNSSELIE DTPQAISNNE LNNANSNTSK RITSNNSNMN
SPNDVNLNSN DTIVDAASNN TINTTHNTAT IPIISTSETS SELDIDPTST PTKINIVPAL
NSITNPKIIE GSQNSQIMSK DISNPISSKT VNNVEFDRIN SNGQKINSTS SSNEETFINK
PSPSENDTLT FKSNKVLNNL TQQLSEVSMS DGQRTSSESS ANNTFESSRK TSISESVDSN
EASPGKLSNN AHNIKRLTNG LQLDSPEKYS VTNSTLPTNQ GSVSQFYEKK EILSNGSKLS
NKDPFVQVNA DSDSPIKQAV TDQFYGNKEV ISNGNTLNNL NHKDQLSRVN TNSKFTSDYE
NNYLNETISN TSTKIFSSTV SPDKIDKTFD TSIDDIKPID EKASQINSTL TSSTRTQQRV
PDTTNRMTKL QRLSSESEDG NLSAKLDRLA SIEISDNFTG ELDIEQEKED SPSQMINTPN
PFEEGFNKFD NRASMSSTVT SNRNTKGSLD EFVDAHSSPA KVVDKKPTLS TLTNTENKNS
VREKIAQLSS KVSEREQQPT SEALRKNIDI TRKNLTEKFI SNGGEQTTSA KPNRSINMRS
MSSSVSVSEM SRKFSNPIDL PSNGTLQNLN NKANKTDEFS SNKATETSIQ SKNIFEFNND
KEILKPQIND EVDTNNSSNL QDTTNTGKEI DVSESSFNDE LNTTVIKNDI TTIENNSSFI
KISNSELPSP HSGSLSISSN NNNNNNNNNN NNNNNNSTNY NNMENSKAVI QRLPENGPEI
AENITPTFIT AKDHNDLDVG DINSRDIFNN PSPTKPKELQ MEINDLNSES SFVSANPELN
PSVTAEEQQG HNIRNNIQKM GLKSIDRINS LKRLKPSNPF ANSIKKEYPN FNIPVVSSEN
ITVSDIDDSG EFQFVPLNNE SQGEIKETGL MQSYSNNPDD SDDFQFIPLR NEIKNEDTYS
SMNMVGSNEI PSINITTKEE DQYSINNEKF PSSLNYKEYH PSIMNKAIHL EEHPSLISKS
NHEERELSTN QISNEESFEF IPKNNINENM GIMNNDSDKV VKENNNNSEE SESESEESES
EENSSDGDDD DDDDDEKNMD EVDSNSNEFD IDSFDIKNPD NTLADLLLYL EHQTVQVIST
IQSLLTSIKQ PNSTKGNLRV EANAINQVIC QMSDATSTSM NQSRNANLKE HGSWVVQSLR
DCSTRMTTLC QLNIDGILTN EQGDKDYADK QFKQRLAGLA FDVAKCTKEL VKSVEEASLK
EEIEYLSSRL DDRNHQIV
//
