ID   I2H3S6_TETBL            Unreviewed;      1323 AA.
AC   I2H3S6;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=K Homology domain-containing protein {ECO:0000259|SMART:SM00322};
GN   Name=TBLA0D05350 {ECO:0000313|EMBL:CCH61028.1};
GN   ORFNames=TBLA_0D05350 {ECO:0000313|EMBL:CCH61028.1};
OS   Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC
OS   10599 / NRRL Y-10934 / UCD 77-7) (Yeast) (Kluyveromyces blattae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX   NCBI_TaxID=1071380 {ECO:0000313|EMBL:CCH61028.1, ECO:0000313|Proteomes:UP000002866};
RN   [1] {ECO:0000313|EMBL:CCH61028.1, ECO:0000313|Proteomes:UP000002866}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 /
RC   UCD 77-7 {ECO:0000313|Proteomes:UP000002866};
RX   PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA   Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA   Wolfe K.H.;
RT   "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT   accidents.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
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DR   EMBL; HE806319; CCH61028.1; -; Genomic_DNA.
DR   RefSeq; XP_004180547.1; XM_004180499.1.
DR   STRING; 1071380.I2H3S6; -.
DR   GeneID; 14496064; -.
DR   KEGG; tbl:TBLA_0D05350; -.
DR   eggNOG; KOG2208; Eukaryota.
DR   HOGENOM; CLU_003293_1_0_1; -.
DR   InParanoid; I2H3S6; -.
DR   OrthoDB; 5489311at2759; -.
DR   Proteomes; UP000002866; Chromosome 4.
DR   GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd22449; KH-I_ScSCP160_rpt4; 1.
DR   Gene3D; 3.30.1370.10; K Homology domain, type 1; 7.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR   Pfam; PF00013; KH_1; 6.
DR   SMART; SM00322; KH; 7.
DR   SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 7.
DR   PROSITE; PS50084; KH_TYPE_1; 7.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002866};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00117}.
FT   DOMAIN          247..325
FT                   /note="K Homology"
FT                   /evidence="ECO:0000259|SMART:SM00322"
FT   DOMAIN          727..799
FT                   /note="K Homology"
FT                   /evidence="ECO:0000259|SMART:SM00322"
FT   DOMAIN          803..868
FT                   /note="K Homology"
FT                   /evidence="ECO:0000259|SMART:SM00322"
FT   DOMAIN          873..948
FT                   /note="K Homology"
FT                   /evidence="ECO:0000259|SMART:SM00322"
FT   DOMAIN          951..1025
FT                   /note="K Homology"
FT                   /evidence="ECO:0000259|SMART:SM00322"
FT   DOMAIN          1029..1097
FT                   /note="K Homology"
FT                   /evidence="ECO:0000259|SMART:SM00322"
FT   DOMAIN          1252..1322
FT                   /note="K Homology"
FT                   /evidence="ECO:0000259|SMART:SM00322"
FT   COILED          929..956
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1224..1252
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1323 AA;  151169 MW;  8502C92EA1E791D0 CRC64;
     MTNFNYIYVY WTNRITAELY LVMPDTIPPQ LRTPSNKFEN VKDIGLDFVL SDLSDDDNEN
     SKSIEIQRDY NSETSSSSIN ESLKNGKSFT NEEIMPKIRL ENSPDLNFKS IAALPHLSNR
     CYLDNNEEGT NWKVQNMEVP KNLPCLISTN AINDDKGIKD FNFKIDKVSK PMISKVIQLS
     FKVKKEDHVS NLTKTKLDNV LVSLMKQFNV KIESTVFKES GDRLFILSGL KEKILESKRL
     LLKNLTKPVS ISFTIPFKTR SAIIGLNGNT IESISKKYSI KINLESKPLE NSFDEYLNDN
     KCNCNLIGDS ESIQLAKLDI LKIVNEQIKD ARFRVCLLEA STTNNNDYSK ILPFINCNKI
     ANNLDRLNKS NARCFFDDRL KTFNIFGNRK DAIEINRKLQ QTLKTRSVLI IEKKIKIPIK
     FQVLINIEEI NKLFGIMVNL SNSWNDESVT FVGEIIKVER AIQFARESSK GLIVDTLDVS
     KSHGGNNLKF TNWLLFYFKK YKDIFERLSH DYNDLVTIYL PNSKLINCAS NSNIYIVAKE
     DNKDQIKHVR KEIINLINQI SPEDVLEITN IDYSLFGFNV KSILNKNSKK IDFVQLGDFI
     DDNNTIILFA KVFNSSNDNK NDFDFKPSDQ EIKTSLLENS RLLDPLIPKI KDIKQQIFEL
     NSNIQDEIFG KGSVSLNLLN EEVSADNGNL SVKFHSPDKN SITLIGTSIG LKLALRALTY
     IKEEPSRYNK KQITIPSHVI PRLVGNKGSH LSELHKKFDV SLDIPQVKNI NQSKPIEITI
     TGLGYNIRRV IHYLNKEVDT WADIITFEKQ VPVELHQKLL GPQNEFRERL QKKYNVKISF
     LKENELVTIR GSTTDVKKAQ KELNNLLDFE IQNNEKIKVQ IPFKLVSKII GKGGEIINGI
     RIDYNVEINS LETTKGKKVE KKGYVDFEII GSKNNIQEAK KKLDSIINES ENISKELDVD
     RKYHNQLIGI NGSILKDIIT KSGGDPSKGR SIIIPPKGSN NNKIIIAGTK EFVESATIEI
     QTLISELENQ TTENITIPKE KHSLIIGTSG IVRQEIEEEF SVILNIPSKN SKSTHVSISG
     LPENIEKAKL KINDILAEFT TTNTKEVIVP AQYQEFVSQH GFFLQTLRFN HNINVKYGSD
     SRRAMKFSKP SFNIPDKKIR TEGLSSKKNI TFTVEKFRDG SNINWKKQKP ISWILEYDPL
     DFNVLEFEDK ELEQLFPEMN GNNNENIKNN ANDALEVAQN ILQNRIELAK RANYAGYIWC
     SNPKRFTKVI GSGGSRINEI RRKTETLIII PRKTKNEKDI IFIRGTEEQV REAGNMILES
     LKN
//