ID I2H5M8_TETBL Unreviewed; 686 AA.
AC I2H5M8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN Name=TBLA0F01370 {ECO:0000313|EMBL:CCH61680.1};
GN ORFNames=TBLA_0F01370 {ECO:0000313|EMBL:CCH61680.1};
OS Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC
OS 10599 / NRRL Y-10934 / UCD 77-7) (Yeast) (Kluyveromyces blattae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX NCBI_TaxID=1071380 {ECO:0000313|EMBL:CCH61680.1, ECO:0000313|Proteomes:UP000002866};
RN [1] {ECO:0000313|EMBL:CCH61680.1, ECO:0000313|Proteomes:UP000002866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 /
RC UCD 77-7 {ECO:0000313|Proteomes:UP000002866};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
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DR EMBL; HE806321; CCH61680.1; -; Genomic_DNA.
DR RefSeq; XP_004181199.1; XM_004181151.1.
DR AlphaFoldDB; I2H5M8; -.
DR STRING; 1071380.I2H5M8; -.
DR GeneID; 14496789; -.
DR KEGG; tbl:TBLA_0F01370; -.
DR eggNOG; KOG1716; Eukaryota.
DR HOGENOM; CLU_365223_0_0_1; -.
DR InParanoid; I2H5M8; -.
DR OrthoDB; 2045814at2759; -.
DR Proteomes; UP000002866; Chromosome 6.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR47550; DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1; 1.
DR PANTHER; PTHR47550:SF1; DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1; 1.
DR Pfam; PF00782; DSPc; 1.
DR SMART; SM00195; DSPc; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 2.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002866}.
FT DOMAIN 492..655
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 577..642
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
SQ SEQUENCE 686 AA; 79836 MW; 4692DEA30E229ADC CRC64;
MAKYISPLNF INEFDAFLKH DLPAINDVRP YLNSTASNNI TFANNFTNVH DSKDDQLQYW
KWNGSILLIR TSHSTENSYR YLTNSVDLRD IYINVPSQSY RKIKLLEIFD VKYNPSRNSE
IQELVEIGST FKVLPCFKND PTFKPHYNVK SHELRRFDLQ ACNFLNIVQK IVLYCNNSCD
IIEDNKKCPK CELAKKFIHS TFNLGGFNAI PEIFILEHDY EPTFLPLQNY KLNRNLIHRE
QIEMTQMTHA TPVDNSIFVG NSYDLDGIHY SPTTDNYPYY NIEYSTIFEK MQLSEKNKSI
TIGESDIHWD ITIECTVANQ QEQNNSNILD SEFDETKSKL KFPGAGSFTL GGLNKTRIEN
ILKYCQFLYI SNMSNKKILV YCRDGYTESS FLIIAFLIFK YSLSLTRAIL TLHDLNRQLF
LYPGDIQVLG HIEPILHDNS PLNQKQQLID INADNNLATK LNIEISSNNF TEIFLTKLPS
NYARLMNIKG PLPSKILPFL YLGSLHNIIY PDILRSLNIT HLINIGSLPP WLNRTNKNTN
KQKYTTSIES YEQYNIKILC LHDLLDNGEM SITGYFDQLI EFINTCKRDS GRIIIQCDMG
VSRSVTIILA YLIKQYKISL IKSYLYLRCR RLNIIIQPSI LFMYELLKWE HLCLNENKTI
DCKTKRSNDW FSLCMEISHL NKIYSA
//
