ID I2H6P1_TETBL Unreviewed; 321 AA.
AC I2H6P1;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=NADP-dependent oxidoreductase domain-containing protein {ECO:0000259|Pfam:PF00248};
GN Name=TBLA0G00960 {ECO:0000313|EMBL:CCH62043.1};
GN ORFNames=TBLA_0G00960 {ECO:0000313|EMBL:CCH62043.1};
OS Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC
OS 10599 / NRRL Y-10934 / UCD 77-7) (Yeast) (Kluyveromyces blattae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX NCBI_TaxID=1071380 {ECO:0000313|EMBL:CCH62043.1, ECO:0000313|Proteomes:UP000002866};
RN [1] {ECO:0000313|EMBL:CCH62043.1, ECO:0000313|Proteomes:UP000002866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 /
RC UCD 77-7 {ECO:0000313|Proteomes:UP000002866};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
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DR EMBL; HE806322; CCH62043.1; -; Genomic_DNA.
DR RefSeq; XP_004181562.1; XM_004181514.1.
DR AlphaFoldDB; I2H6P1; -.
DR STRING; 1071380.I2H6P1; -.
DR GeneID; 14497459; -.
DR KEGG; tbl:TBLA_0G00960; -.
DR eggNOG; KOG1575; Eukaryota.
DR HOGENOM; CLU_023205_2_0_1; -.
DR InParanoid; I2H6P1; -.
DR OMA; KFGVVKM; -.
DR OrthoDB; 5357470at2759; -.
DR Proteomes; UP000002866; Chromosome 7.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:UniProt.
DR CDD; cd19079; AKR_EcYajO-like; 1.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR43364:SF15; ARYL-ALCOHOL DEHYDROGENASE AAD16-RELATED; 1.
DR PANTHER; PTHR43364; NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002866}.
FT DOMAIN 14..312
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
SQ SEQUENCE 321 AA; 37257 MW; 6538163212655145 CRC64;
MTFGNKGWHK WVIDDKQKSY KILKRAYDLG LRTYDTADLY SNGQSEIIIL GEFLKEYNIS
RETVVIMTKL FAPVDDTLPD YQPTGGLHGN QTIHFANQRG LSKKHIIEAC KNSLRRLGTY
IDVYQVHRAD PDTPMEETMR ALNDVVQQGL TRYIGASSML GTKFAEYQFI AEKNGWSKFV
NMQDCYNLLY REEEREMIPY IKKHGIAQTP WSPLQRGLLS RPVEGSSYRE DNDRVLKGQR
LNQYEDFEIE IIKRVEEISK KRNNPMAVIS TAWVLSKGTF PILGLNSVER MEDAVRALNI
ELTEEELKYL EEPYKPKKLV Q
//
