ID I2H806_TETBL Unreviewed; 307 AA.
AC I2H806;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=Prohibitin {ECO:0000256|RuleBase:RU366048};
GN Name=TBLA0H02220 {ECO:0000313|EMBL:CCH62508.1};
GN ORFNames=TBLA_0H02220 {ECO:0000313|EMBL:CCH62508.1};
OS Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC
OS 10599 / NRRL Y-10934 / UCD 77-7) (Yeast) (Kluyveromyces blattae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX NCBI_TaxID=1071380 {ECO:0000313|EMBL:CCH62508.1, ECO:0000313|Proteomes:UP000002866};
RN [1] {ECO:0000313|EMBL:CCH62508.1, ECO:0000313|Proteomes:UP000002866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 /
RC UCD 77-7 {ECO:0000313|Proteomes:UP000002866};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|RuleBase:RU366048}.
CC -!- SIMILARITY: Belongs to the prohibitin family.
CC {ECO:0000256|ARBA:ARBA00009658, ECO:0000256|RuleBase:RU366048}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HE806323; CCH62508.1; -; Genomic_DNA.
DR RefSeq; XP_004182027.1; XM_004181979.1.
DR AlphaFoldDB; I2H806; -.
DR STRING; 1071380.I2H806; -.
DR GeneID; 14497665; -.
DR KEGG; tbl:TBLA_0H02220; -.
DR eggNOG; KOG3090; Eukaryota.
DR HOGENOM; CLU_047969_0_2_1; -.
DR InParanoid; I2H806; -.
DR OMA; NEGTHFQ; -.
DR OrthoDB; 1330394at2759; -.
DR Proteomes; UP000002866; Chromosome 8.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03401; SPFH_prohibitin; 1.
DR Gene3D; 3.30.479.30; Band 7 domain; 1.
DR InterPro; IPR001107; Band_7.
DR InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR InterPro; IPR000163; Prohibitin.
DR PANTHER; PTHR23222; PROHIBITIN; 1.
DR PANTHER; PTHR23222:SF1; PROHIBITIN-2; 1.
DR Pfam; PF01145; Band_7; 1.
DR PRINTS; PR00679; PROHIBITIN.
DR SMART; SM00244; PHB; 1.
DR SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU366048};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792,
KW ECO:0000256|RuleBase:RU366048};
KW Reference proteome {ECO:0000313|Proteomes:UP000002866};
KW Transmembrane {ECO:0000256|RuleBase:RU366048};
KW Transmembrane helix {ECO:0000256|RuleBase:RU366048}.
FT TRANSMEM 36..57
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366048"
FT DOMAIN 55..216
FT /note="Band 7"
FT /evidence="ECO:0000259|SMART:SM00244"
SQ SEQUENCE 307 AA; 34272 MW; 2C229C3E7D5D00CA CRC64;
MNNRPNDFQK FAQDLQSRLA NIQRTKQSKI PRRSNIVGLL GLIALGGGAL LFNSSLFNVD
GGHRAILYSR LSGVSSKIYN EGTHFVIPWL QTPIIYDVRA KPRNVASLTG TKDLQMVNIT
CRVLSRPDIP SLPLIYRTLG QDYDERVLPS IVNEVLKAVV AQFNASQLIT QRDKVSRLIR
ENLVRRAGKF NIALDDVSIT FMTFSPEFTN AVESKQIAQQ DAQRAAFLVD RARQEKQGMV
VKAQGEAKSA ELIGEAIKKS KDYVELKRLD ISKDIAKILA TSSNRLVLDN EALLLNTQLD
ARGEHSK
//
