ID I2JHW0_9GAMM Unreviewed; 226 AA.
AC I2JHW0;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Deoxynucleoside kinase family protein {ECO:0000313|EMBL:EIF42562.1};
GN ORFNames=DOK_13274 {ECO:0000313|EMBL:EIF42562.1};
OS gamma proteobacterium BDW918.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC Spongiibacteraceae.
OX NCBI_TaxID=1168065 {ECO:0000313|EMBL:EIF42562.1, ECO:0000313|Proteomes:UP000003473};
RN [1] {ECO:0000313|EMBL:EIF42562.1, ECO:0000313|Proteomes:UP000003473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BDW918 {ECO:0000313|EMBL:EIF42562.1,
RC ECO:0000313|Proteomes:UP000003473};
RX PubMed=22740675; DOI=10.1128/JB.00678-12;
RA Kim S.M., Cho S.J., Lee S.B.;
RT "Genome Sequence of the Unclassified Marine Gammaproteobacterium BDW918.";
RL J. Bacteriol. 194:3753-3754(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIF42562.1}.
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DR EMBL; AJMK01000067; EIF42562.1; -; Genomic_DNA.
DR AlphaFoldDB; I2JHW0; -.
DR PATRIC; fig|1168065.3.peg.2728; -.
DR eggNOG; COG1428; Bacteria.
DR HOGENOM; CLU_030466_2_0_6; -.
DR OrthoDB; 9776634at2; -.
DR Proteomes; UP000003473; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019136; F:deoxynucleoside kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01673; dNK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002624; DCK/DGK.
DR InterPro; IPR031314; DNK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10513:SF46; DEOXYGUANOSINE KINASE; 1.
DR PANTHER; PTHR10513; DEOXYNUCLEOSIDE KINASE; 1.
DR Pfam; PF01712; dNK; 1.
DR PIRSF; PIRSF000705; DNK; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW Kinase {ECO:0000313|EMBL:EIF42562.1};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000003473};
KW Transferase {ECO:0000313|EMBL:EIF42562.1}.
FT DOMAIN 21..209
FT /note="Deoxynucleoside kinase"
FT /evidence="ECO:0000259|Pfam:PF01712"
FT ACT_SITE 99
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-1"
FT BINDING 25..33
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
FT BINDING 151..155
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
SQ SEQUENCE 226 AA; 26448 MW; 59AE449C7B05EFC5 CRC64;
MTNHNLLNEP IINLQHPPRF IAVEGPIGVG KTTLARRLAE SLNFHQLLEK AEENPFLERF
YANQRHAALS AQLFFLFQRA QQLSDLRQSD LFEQTHVADF VFQKDPLFAK ITLDNNELEL
YNKVYEQVQV DIPTPDLVIY LQAPVKVLKD RIQQRGVAFE RSIDAEYLEK INGAYSEYFH
SYHDSPLLII NASEIDFANN DQQYEQLLQY LLEIRSGRHY FNPTFF
//
