ID I2JUA5_DEKBR Unreviewed; 528 AA.
AC I2JUA5;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:EIF46557.1};
GN ORFNames=AWRI1499_3518 {ECO:0000313|EMBL:EIF46557.1};
OS Brettanomyces bruxellensis AWRI1499.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Brettanomyces.
OX NCBI_TaxID=1124627 {ECO:0000313|EMBL:EIF46557.1, ECO:0000313|Proteomes:UP000004997};
RN [1] {ECO:0000313|EMBL:EIF46557.1, ECO:0000313|Proteomes:UP000004997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AWRI1499 {ECO:0000313|EMBL:EIF46557.1,
RC ECO:0000313|Proteomes:UP000004997};
RX PubMed=22470482; DOI=10.1371/journal.pone.0033840;
RA Curtin C.D., Borneman A.R., Chambers P.J., Pretorius I.S.;
RT "De-Novo Assembly and Analysis of the Heterozygous Triploid Genome of the
RT Wine Spoilage Yeast Dekkera bruxellensis AWRI1499.";
RL PLoS ONE 7:E33840-E33840(2012).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIF46557.1}.
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DR EMBL; AHIQ01000202; EIF46557.1; -; Genomic_DNA.
DR Proteomes; UP000004997; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07091; ALDH_F1-2_Ald2-like; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000004997}.
FT DOMAIN 56..516
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 293
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 528 AA; 56877 MW; A025B412E4C5E313 CRC64;
MFRYTAAKAF SAASRAALKP TMASRFYSSS KLSKTITLPT GETYEQPTGL FINNEFVSGK
QGKTFGVINP STEEEICEVA EAMPEDVDSA VDAAEKAFNS DWSSGDPANR GKVLYNLADL
MEAHKKTLTS IESLDNGKTL ANAAGDVGLV INYLRFCAGY ADKLDGEVVD TGSGYLNLVK
REPLGVCGQI IPWNFPLLMW SWKIGPALAT GNTVVLKPAE ATPLSALYSA KLAKEAGVPA
GVLNIVSGFG KTTGEAIATH PRIRKVAFTG STRTGKHIMT AAAQSNIKKV TLELGGKSAN
IVFNDCNVDK TIQNIITGIF FNSGEVCCAG SRIFIQSGIY DTIIEKLKTA VQAIKVGNPF
DPAVFQGAQT SQMQLDKILG YVEKGKEEGA HLLTGGEREG NKGYFIKPTL FTEAKPGMAI
YEEEIFGPFG VITKFDTPDE ALXLANNSEY GLAAGIHTEN LNTAKYVSDR LRAGTVWINT
YNDFHYAVPF GGYKQSGIGR EMGKSSFDNY TQVKAIRTKI DETVGTKQ
//
