ID   I2JZH1_DEKBR            Unreviewed;       390 AA.
AC   I2JZH1;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Rho gtpase activating protein {ECO:0000313|EMBL:EIF48373.1};
GN   ORFNames=AWRI1499_1680 {ECO:0000313|EMBL:EIF48373.1};
OS   Brettanomyces bruxellensis AWRI1499.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Pichiaceae; Brettanomyces.
OX   NCBI_TaxID=1124627 {ECO:0000313|EMBL:EIF48373.1, ECO:0000313|Proteomes:UP000004997};
RN   [1] {ECO:0000313|EMBL:EIF48373.1, ECO:0000313|Proteomes:UP000004997}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AWRI1499 {ECO:0000313|EMBL:EIF48373.1,
RC   ECO:0000313|Proteomes:UP000004997};
RX   PubMed=22470482; DOI=10.1371/journal.pone.0033840;
RA   Curtin C.D., Borneman A.R., Chambers P.J., Pretorius I.S.;
RT   "De-Novo Assembly and Analysis of the Heterozygous Triploid Genome of the
RT   Wine Spoilage Yeast Dekkera bruxellensis AWRI1499.";
RL   PLoS ONE 7:E33840-E33840(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EIF48373.1}.
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DR   EMBL; AHIQ01000092; EIF48373.1; -; Genomic_DNA.
DR   Proteomes; UP000004997; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd00159; RhoGAP; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR45808; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR   PANTHER; PTHR45808:SF2; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR   Pfam; PF00620; RhoGAP; 2.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000004997}.
FT   DOMAIN          137..390
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          250..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   390 AA;  43584 MW;  9FDDC7F0DF5527DB CRC64;
     MISAQSLGPL DTHNVCTAPS PESTPIGSIX STVDNSAXSX XFSKPRRLVF HPLTFNNEMK
     NPNSKSATPR RISISGPLRV QTTNEYLLSS KTPTFTRSAS SLSYGSSRKV VSSPCTGLVL
     NNATLIASAP SACTIFNRLD NELRKSYSEV DFCDGCKVTV PTIVSRCIQF LESRDPVEGV
     FRINGSIRKI KSIETAIQXQ GIDSFRFENF TFENNETPNC YDVAMVLKRW LANLENGLIT
     SQINAKLKRD RMSSKDDMFD EADEPREEEQ NTSRATHEEE DTTLVDLSTN TVLIRDQNSY
     HPHNTLLSNT ISDSPNSSMV SSVTTDSDSN SPKFYDFTAR RLSELPIENL HLFLYLLKFL
     NRMTADSIVH ITKMTATNLA KIFQLSFFXK
//