ID I3CEN7_9GAMM Unreviewed; 471 AA.
AC I3CEN7;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Transcriptional regulator with HTH domain and aminotransferase domain {ECO:0000313|EMBL:EIJ42080.1};
GN ORFNames=BegalDRAFT_1178 {ECO:0000313|EMBL:EIJ42080.1};
OS Beggiatoa alba B18LD.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Thiotrichaceae; Beggiatoa.
OX NCBI_TaxID=395493 {ECO:0000313|EMBL:EIJ42080.1, ECO:0000313|Proteomes:UP000005744};
RN [1] {ECO:0000313|EMBL:EIJ42080.1, ECO:0000313|Proteomes:UP000005744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B18LD {ECO:0000313|EMBL:EIJ42080.1,
RC ECO:0000313|Proteomes:UP000005744};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Held B., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Pagani I., Samuel K., Teske A.,
RA Mueller J., Woyke T.;
RT "Improved High-Quality Draft sequence of Beggiatoa alba B18lD.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; JH600070; EIJ42080.1; -; Genomic_DNA.
DR RefSeq; WP_002684660.1; NZ_JH600070.1.
DR AlphaFoldDB; I3CEN7; -.
DR STRING; 395493.BegalDRAFT_1178; -.
DR eggNOG; COG1167; Bacteria.
DR HOGENOM; CLU_017584_0_0_6; -.
DR Proteomes; UP000005744; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF2; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:EIJ42080.1};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000005744};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:EIJ42080.1}.
FT DOMAIN 13..81
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT COILED 369..396
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 471 AA; 52466 MW; 64DFD2FF32EFFE84 CRC64;
MMSLVSLDSQ DTMPLIEQIV KGIQQQVDAR VLRTGARLPS IRKFAEVHSI SRFTVVQAYD
RLVASGYLES RKGSGFFVTK PLSADPPIAE HSAQLERAVD VLWLLHQSFQ NTAHFASPGC
GWLPSEWRDD ASLQKAIRTV SRHNDYTSGG YGNIYGYVPL RQDLQKRLAE LGIVTNLQNI
LTTHGVTQGI DLVGRYLIQA GDNVLVDDPG YYSLFGHLKL LGAKLVGVPR TLDGVDTQAM
ETLIQLHRPK IFITNTVLHN PTGTSLSQAN AHRVLQLAEK YDLLIIEDDV YGDFSPPSVS
RLATLDHLNR VIYLSSFSKT ITTSVRVGFL AARADIVQAL GDLKLLTSLT TSETNERVIH
QVLIDGYYRK HLEKLRARVQ NAREKAMRQL EKAGLEIFAE TEHGLFIWAK LPDCHDAAKI
ASIATKRGIM LAPGNVFRPH QEPSPWLRFN AAYCDNPAIF QFLAEFNDIS G
//
