ID I3CHW0_9GAMM Unreviewed; 1043 AA.
AC I3CHW0;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Cation/multidrug efflux pump {ECO:0000313|EMBL:EIJ43203.1};
GN ORFNames=BegalDRAFT_2349 {ECO:0000313|EMBL:EIJ43203.1};
OS Beggiatoa alba B18LD.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Thiotrichaceae; Beggiatoa.
OX NCBI_TaxID=395493 {ECO:0000313|EMBL:EIJ43203.1, ECO:0000313|Proteomes:UP000005744};
RN [1] {ECO:0000313|EMBL:EIJ43203.1, ECO:0000313|Proteomes:UP000005744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B18LD {ECO:0000313|EMBL:EIJ43203.1,
RC ECO:0000313|Proteomes:UP000005744};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Held B., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Pagani I., Samuel K., Teske A.,
RA Mueller J., Woyke T.;
RT "Improved High-Quality Draft sequence of Beggiatoa alba B18lD.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH600070; EIJ43203.1; -; Genomic_DNA.
DR RefSeq; WP_002690184.1; NZ_JH600070.1.
DR AlphaFoldDB; I3CHW0; -.
DR STRING; 395493.BegalDRAFT_2349; -.
DR eggNOG; COG0841; Bacteria.
DR HOGENOM; CLU_002755_1_2_6; -.
DR OrthoDB; 5613295at2; -.
DR Proteomes; UP000005744; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF28; BLR2861 PROTEIN; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005744};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 460..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 521..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 850..869
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 876..896
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 902..923
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 944..967
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 979..1005
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1043 AA; 115091 MW; 57C1F87F54C11E6C CRC64;
MVLSEMSIRR PVLATVMSLM IILVGALSFT RLSVREYPNI DAPVVSVRTV YTGASAEIME
SQVTQPIEDA LAGIEGIKKI KSISREQVSE ITIEFVLTRD ADNAANDVRD RVARARSELP
DESDEPVVSK VEADAQAVVW IAFSSDKHSS LELSDYADRF IIPRLQVLEG VASVIIGGER
RYAMRIWLDR DRLAAYKLTP QDVESALRLQ NIEIPSGRIE STQREFTVLT QTDLKTPQEF
NDLIIKEVNG YPIRLSDVGK AEVGPEDERR IVRVNGQSAV GLGVVKQSTA NTLSVAQAVR
AELPRVSVLD GMKLEVVFDT SIFIEASIDA VYRTMTEAFI LVVLVIFAFL RSFRVTFIPF
VTIPVSLIGA FIFLDVLGFS INILTLLGLV LAIGIVVDDA IVMLENIHRH VELGKPPLQA
AVAGSREIGF AVISMTVTLA AVFVPLTFMT GNTGRLFTEF ALTVSAAVVV SGFVALTLTP
MMCSKMFKSH EHHGFLFNIT EKFFVAMNDG YRFVLKGVLK VWWLMLVVFA VTIYGAIWIY
PQIKQELAPT EDRSILIGVL SAPEGATLEY TDKYARQIEK IYEKVPEIRK FFVVVAPGLQ
NPNPVNNALS FVSLIPWGER TRSQQAIAAE VMPKMLSLPG VLAFALNPPS LGQSFRNPPV
QFIIQGDSYE QLQTMSDNML AKIRAYPGMT NVDTDLKLNK PQLVVSIDRD KVAAVGVEVE
EVGRTLETLL GGRQVTRFKR EGKQYDVIVQ LSQEDRTKPA DLSSIFVRNK NGQLIQLSNL
VTVTEAVAPK ELNRFDRLRA VLISANVAPG YSLKQALDFL DQTAKETLDA TAKTGLDGQS
REFKESGETL VMTFILALIF IYLVLAAQFE SFISPFIIML TVPLAMTGAL FALFYTNGTL
NVYSQIGLVM LIGLITRHGI LIVEFANQLQ EQGKLLKEAV VEAAVLRLRP ILMTSLSMIL
GTLPLAISVG AGAESRQQIG WVILGGLILG TFLTLFIIPV AYTLLAKRYN PDKEYSHKHG
HKNATYAPHS IVETGGYGNV ERH
//
