ID I3EH44_NEMP3 Unreviewed; 807 AA.
AC I3EH44;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=NEQG_01231 {ECO:0000313|EMBL:EIJ88541.1};
OS Nematocida parisii (strain ERTm3) (Nematode killer fungus).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Nematocida.
OX NCBI_TaxID=935791 {ECO:0000313|EMBL:EIJ88541.1, ECO:0000313|Proteomes:UP000002872};
RN [1] {ECO:0000313|EMBL:EIJ88541.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ERTm3 {ECO:0000313|EMBL:EIJ88541.1};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cuomo C., Troemel E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.,
RA Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Nematocida parisii strain ERTm3.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR EMBL; GL870878; EIJ88541.1; -; Genomic_DNA.
DR AlphaFoldDB; I3EH44; -.
DR STRING; 935791.I3EH44; -.
DR EnsemblFungi; EIJ88541; EIJ88541; NEQG_01231.
DR VEuPathDB; MicrosporidiaDB:NEQG_01231; -.
DR HOGENOM; CLU_018828_0_0_1; -.
DR InParanoid; I3EH44; -.
DR OMA; GMFEYSG; -.
DR Proteomes; UP000002872; Unassembled WGS sequence.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041123; CRM1_repeat.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF18777; CRM1_repeat; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002872}.
FT DOMAIN 34..100
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 807 AA; 90817 MW; A6144AC6BDAFAC00 CRC64;
MEKLLECTDE FDVELFDFVI KTFYDPMDKE HKRAETVLLR YREHPDSWAH TAAVVKDSRD
PRAKVFAVQV LERAVKIRWT MLTEEQKKGA REYVVDKILD LATQTQAESK VLVKQFNQVL
IEIIKREWPE KWPTLIGDLL DASKGDCSVC ANSFNLLALL CDTVFNFNES LVSERVSALQ
AQMKNELGSI YEMVVNILEK VSSGEIYVPN DLTISSLNLL LIMVPQLPAE CLFQPALLDV
VVKYIESEFA THAVQVIRSV FTRKEACTST EAFIGVLRKC FVGVGAFFEK YFRMFNASHT
GGIKAHYASF LPKDVNLIRE VVLFYGIAYK YCKELEKTPC NTTIPLQLML EISQVTDFEL
FRLCLEFWSM FVKDLFLEFP FVPAPSKPPA GLRRTHYTEI LSSLVPVLVA QMQRPEEVII
AENEDGEIIL EKLVDTESIQ HHKEMNELVY HISSMTPGGL GPYFCSEINK LRTGKWTRDR
LNKVSWAAGS IAGTSSPMGE KEFLTQSIQG LLAMCEEADE EGNRAVVASC LMYILVRNPL
YLKTYPLLLE AICNKMLQFI IDVDLVGVSE MACDTLLKIM SSCHDVLRVP LAAGKQCYIL
DVFPHMPKLL NVLKPYLAEV LFEALSYLSE EHIDKLLHLP LMDLFTPVLD SADSIHKVVR
AVRLIKVVCT VEISEEFSSS REPVIGKALS QVHAIYSALP NGAVQPAVLN RSLIILRKEI
LSVYTTIGRT FSINFILGEF MSLWSQVFAC PLTVDAPAAI EKLGLLAELS KRTVEGTASL
VESVSAAIAP QVFAAPEERE EEMKAVL
//
