ID I3IQ80_9BACT Unreviewed; 1231 AA.
AC I3IQ80;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Mechanosensitive ion channel {ECO:0008006|Google:ProtNLM};
GN ORFNames=KSU1_D0566 {ECO:0000313|EMBL:GAB63875.1};
OS Candidatus Jettenia caeni.
OC Bacteria; Planctomycetota; Candidatus Brocadiia; Candidatus Brocadiales;
OC Candidatus Brocadiaceae; Candidatus Jettenia.
OX NCBI_TaxID=247490 {ECO:0000313|EMBL:GAB63875.1, ECO:0000313|Proteomes:UP000002985};
RN [1] {ECO:0000313|EMBL:GAB63875.1, ECO:0000313|Proteomes:UP000002985}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22673575; DOI=10.1016/j.febslet.2012.04.041;
RA Hira D., Toh H., Migita C.T., Okubo H., Nishiyama T., Hattori M.,
RA Furukawa K., Fujii T.;
RT "Anammox organism KSU-1 expresses a NirK-type copper-containing nitrite
RT reductase instead of a NirS-type with cytochrome cd1.";
RL FEBS Lett. 586:1658-1663(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAB63875.1}.
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DR EMBL; BAFH01000004; GAB63875.1; -; Genomic_DNA.
DR AlphaFoldDB; I3IQ80; -.
DR STRING; 247490.KSU1_D0566; -.
DR eggNOG; COG3264; Bacteria.
DR Proteomes; UP000002985; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002985};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 568..585
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..667
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 673..690
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 725..743
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 749..768
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 789..811
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 823..844
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 877..899
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 948..967
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 988..1011
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1017..1046
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1033..1100
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 1111..1191
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
FT COILED 92..133
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 250..328
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 420..473
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1231 AA; 141161 MW; FB894D4C6AD37016 CRC64;
MAQTPEKKSD EVKSAEIGIT VKSEDVEKAR LKAKEIKAIV DKSVKENESL ISDLQRDRDT
TIVYLKKLQQ DKKTYQTEGE NPKFLQLLDK EIDIIKEKLN VSDEQIETYE DQITALQNQL
KAYTDQVALL ETIAKLEEII AVTPFDQALV VKKELDIAKG YIATVHASLK ERDTIVSFFT
HELEDVKVRV SDREKDLIKD LELQKKDISD EELLKKIQEK IDSIIVWRKA IGAQWIVIFK
TRLGTAKVRY DQIIQILKNA ELNIAFLAEK ANRLEEKLRS EELKKKQAEL EAAKRAEEVN
QKIAEMRRAE AEKALQEAIR KAEEVAQKQM VTTSPEKKRV LELEAELHKQ TGLVARKKDE
LITEGEQRYK DATEYKELEA DIEFFLERRM TASVIDEFLR KTESDIQRFS NAITVIESLI
TSVKREEKLF LDNLKNAQEE ISKIEKEIAV FENKELARQI KEYAHQKIEI HEELTKLLSA
ILDRLHERLE IKNNALALSN RTREKLITMR AANIWARIES NISTETFKTI YKDLIQSRLL
FDTFYNTAQN AVKNFILYLD TEKKTVSFWI RLCGLLVILA GLYFSKRFLC MWCTSKIEES
YEATHAENGS DVLAAGDEIT SKIEESYKVT DISYYKSRLL PSLLLIMKKS IGAFWIAILS
FSLTSLFHIR VPWVTATVYI LTYFAVYKIL KSFLIESFGP EKGDKKLVTS LAYVSPTHLY
RSLNIMLLFS LISLSAITVL TVFEYRNDVI KLLWFVYRLG MLILLLWLAT QRTFILKLLP
SGEGKLGKFI HRVIVIIYPI FITFVISLFA IRSLGYSVLT YALLKTCIKS FIVAFIVFLV
WKYLQHRLDY IRDARLRKKM IQKGTSEEKK FHAITSVYSV SCKYAISLIA AIIIIRVWVR
TFYDALGSPA APYLVQKIFG QIGAVLGTLR SGLSYRFVFE DGKYTTPIKI IVAFAIFLVF
FFIARYIKKL LEERVFYKLR LERGARQTFS SLIRYVIVGI AALIGLNLAG IPLKSLTIFA
GAFGIGIGFG MQNIISNFVS GIILLFERPM RVGDVVILDD GTGGTIESIN ARSTTLTTPD
GVTITVPNAK FIENRITNWT LPTPLMRGCV KVGVAYGSDT GLVKQCLLEI AKQNPNVKVY
PEPVVRFAEF GENALRFELY FWADDPGKRW FTMSELNFAI DKVFKQNNIE IAFPQHDIHI
RSIVPFPVPD KDKKEIVTAD IENIVYKRNN A
//
