ID I3IUJ4_ORENI Unreviewed; 492 AA.
AC I3IUJ4;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Solute carrier family 7 member 11 {ECO:0000313|Ensembl:ENSONIP00000000284.1};
GN Name=slc7a11 {ECO:0000313|Ensembl:ENSONIP00000000284.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000000284.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000000284.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_005466062.1; XM_005466005.3.
DR AlphaFoldDB; I3IUJ4; -.
DR STRING; 8128.ENSONIP00000053440; -.
DR Ensembl; ENSONIT00000000283.2; ENSONIP00000000284.1; ENSONIG00000000223.2.
DR GeneID; 100697391; -.
DR KEGG; onl:100697391; -.
DR CTD; 23657; -.
DR eggNOG; KOG1287; Eukaryota.
DR GeneTree; ENSGT00940000166427; -.
DR OrthoDB; 1103451at2759; -.
DR TreeFam; TF313355; -.
DR Proteomes; UP000005207; Linkage group LG2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR PANTHER; PTHR11785; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR11785:SF323; CYSTINE_GLUTAMATE TRANSPORTER; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 492 AA; 54208 MW; 75051C9931DD07E5 CRC64;
MTGSSASAHR ETAANGHKVS SNGTEQKDRK VELGKKVTLL RGISIIIGTI IGAGIFISPK
GILKHSGSVG VSLLVWIACG VLSLFGALSY AELGTCIKKS GGHYTYIMEA FGPQMAFIRL
WADLIAIRPA GMAVISLAFG QYILEPLFMP CGIPPLAVKL ATAIGLTSVM YLNSMSVTWT
ARIQIFLTVS KLLAIAIIIV PGMYQLFKGE TRHFENAFDL SNVQLSGMPL AFYSGMYAYA
GWFYLNFVTE EVNNPAKTVP LAICISMAIV TSCYVLTNVA YYTVMSAEEL LASSAVAVTF
AERLLGNFSI AVPVFVALSC YGSMNGCIFA LSRMFYVASR EGQLPEVLSM IHVRRHTPLA
AVLIMYPMTM LQLLVGDIYS LLNFMSFLRW LFIGVVVLGL IYLRYTKPDL PRPFKVPLFF
PVVFCITCFF MVFLSLYSDP VNTGIGFAIS LTGIPAYYIF IYFNHRPKWL QRTLDSFNRT
MQIILEVVPA DQ
//
