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Database: UniProt
Entry: I3IYG4_ORENI
LinkDB: I3IYG4_ORENI
Original site: I3IYG4_ORENI 
ID   I3IYG4_ORENI            Unreviewed;      2020 AA.
AC   I3IYG4;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   20-JUN-2018, entry version 54.
DE   SubName: Full=Kinesin family member 13Bb {ECO:0000313|Ensembl:ENSONIP00000001654};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000001654, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Ensembl:ENSONIP00000001654}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2012) to UniProtKB.
RN   [2] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=25186727; DOI=10.1038/nature13726;
RA   Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA   Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J.,
RA   Johnson J., Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J.,
RA   Amemiya C., Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A.,
RA   Bloomquist R., Carleton K.L., Conte M.A., D'Cotta H., Eshel O.,
RA   Gaffney L., Galibert F., Gante H.F., Gnerre S., Greuter L., Guyon R.,
RA   Haddad N.S., Haerty W., Harris R.M., Hofmann H.A., Hourlier T.,
RA   Hulata G., Jaffe D.B., Lara M., Lee A.P., MacCallum I., Mwaiko S.,
RA   Nikaido M., Nishihara H., Ozouf-Costaz C., Penman D.J., Przybylski D.,
RA   Rakotomanga M., Renn S.C., Ribeiro F.J., Ron M., Salzburger W.,
RA   Sanchez-Pulido L., Santos M.E., Searle S., Sharpe T., Swofford R.,
RA   Tan F.J., Williams L., Young S., Yin S., Okada N., Kocher T.D.,
RA   Miska E.A., Lander E.S., Venkatesh B., Fernald R.D., Meyer A.,
RA   Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA   Di Palma F.;
RT   "The genomic substrate for adaptive radiation in African cichlid
RT   fish.";
RL   Nature 513:375-381(2014).
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00283, ECO:0000256|SAAS:SAAS00583243}.
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DR   EMBL; AERX01005741; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AERX01005742; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 8128.ENSONIP00000001654; -.
DR   Ensembl; ENSONIT00000001653; ENSONIP00000001654; ENSONIG00000001311.
DR   eggNOG; KOG0241; Eukaryota.
DR   eggNOG; COG5059; LUCA.
DR   GeneTree; ENSGT00890000139327; -.
DR   InParanoid; I3IYG4; -.
DR   OMA; QLCGMAI; -.
DR   OrthoDB; EOG091G0091; -.
DR   TreeFam; TF105221; -.
DR   Proteomes; UP000005207; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   CDD; cd00060; FHA; 1.
DR   Gene3D; 2.30.30.190; -; 1.
DR   Gene3D; 3.40.850.10; -; 1.
DR   InterPro; IPR036859; CAP-Gly_dom_sf.
DR   InterPro; IPR000938; CAP-Gly_domain.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR022164; Kinesin-like.
DR   InterPro; IPR027640; Kinesin-like_fam.
DR   InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR   InterPro; IPR032405; Kinesin_assoc.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   PANTHER; PTHR24115; PTHR24115; 2.
DR   Pfam; PF01302; CAP_GLY; 1.
DR   Pfam; PF12473; DUF3694; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF12423; KIF1B; 1.
DR   Pfam; PF00225; Kinesin; 1.
DR   Pfam; PF16183; Kinesin_assoc; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM01052; CAP_GLY; 1.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF49879; SSF49879; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF74924; SSF74924; 1.
DR   PROSITE; PS00845; CAP_GLY_1; 1.
DR   PROSITE; PS50245; CAP_GLY_2; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW   ECO:0000256|SAAS:SAAS00875240}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005207};
KW   Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW   ECO:0000256|SAAS:SAAS00874078};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT   DOMAIN       10    358       Kinesin motor. {ECO:0000259|PROSITE:
FT                                PS50067}.
FT   DOMAIN     1915   1957       CAP-Gly. {ECO:0000259|PROSITE:PS50245}.
FT   NP_BIND     108    115       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00283}.
FT   COILED      369    393       {ECO:0000256|SAM:Coils}.
FT   COILED      395    415       {ECO:0000256|SAM:Coils}.
FT   COILED      628    648       {ECO:0000256|SAM:Coils}.
FT   COILED      759    779       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2020 AA;  223408 MW;  CCFCA1133C028941 CRC64;
     MDDNSLSDSN VKVAVRVRPM NRREKDLKTK CVVEMDGNQT VLHPAVTSMN TADPRNQPKV
     FAYDYCFWSM DDSQKDKFAG QDVVFQCLGE SLLDNAFMGY NACIFAYGQT GSGKSYTMMG
     SSEQPGLIPR LCSSLFSRTE KEAREGESFT VEVSYMEIYN EKVRDLLDPK GSRQALKVRE
     HKVLGPYVDG LSRLAVTSYK DIESLMSEGN KSRTVAATNM NEESSRSHAV FNIILTHTLT
     DLRSGTSGEK VSKLSLVDLA GSERAAKTGA AGERLKEGSN INKSLSTLGL VISALADHGA
     GKNKSKFVPY RDSVLTWLLK DSLGGNSRTA MVATISPAAD NYDETLSTLR YADRAKNIVN
     HAVVNEDPNA RIIRELREEV EKLKEQLTEA ESMKAPELKE RLEESEKLIQ DMTVTWEDKL
     RKTEAIAQER QRQLESLGIS LQSSGIRVVD DKCYLVNLNA DPALNELLVY YLKDHTRVGS
     ADSQDIQLCG MAIQAEHCVI DVTESHGVEL TPHRNAKTYV NGTEVVNPVQ LHHGDRILWG
     NNHFFRINLP RHKVQKGGED EEGAAMTKCS SSDCLEVGEL DAYSDVSSER SFGYEFAQAE
     VMMKGVWNND PLQSVLQTLE KQHQEEKRCA LERQRQMYEQ ELQQLRQRVT PEKPSGVPGS
     ATAAVMSASS NKRVRRWSED REAMITRSLR RLKEQIVRAR LLAQEAGFIA EELNKRTEYL
     VTLQIPAANL DANRKRDAVL SEPAIQVRRK SKGKQIWALE KMENRLVDMR ELYQEWKELD
     EDNPVMRSYF KRADPFFDEQ ENHSLIGVAN VFLACLFYDV KLQYAVPIIN QKGEVAGRLH
     VEVWRGTESL EEEGGGGPDK QLSSTDGDER RLCCVVKILQ ATGLPRHLSN FVFCQYHFWA
     QEEPVFTAPE VASSSSASAS RDPQCTVVFD STKELSVPVS EDFVEFLAEG AVAIEVYGHK
     QANHRRNLAL WDLGVIQAKT RSLRERWSEV TRQLELWVKV MELNEAGEFT AVEVVPAKDV
     RTGGIFQLRQ GQSRRVQVEV RPVPDSGTMP LVAASILSVS IGDVKVRQVR LPKNDPKQGT
     DEEMDSYQEV DLERMREQWL VTLTQRQEYL DQQLQKIVCK ADKSEDDVER ESQLLECRLT
     LTEERNAVMV PSAGSGIPGA PVERVPVPGM ETHTPVLFLD LSADDFQSSL SAPLAGGQDA
     LLSGEDEDDF FDLHIVKHYD PEVKAEASWD STVHECPQLS RVAPADQRVY LTLRTVVQLS
     HPAHMQLVLR KRICVSVTGR QGFAQSLLKR MSQRSTVSGC GITFEVVSNI PGDIHGPEDR
     EMLARLAASA EDEQSAASEA AIEKYLRSVL AVENILTLDR LRQEVAVREQ LAGRGKAARR
     CLSSPNIDRL SGSSLDLGSS PLKLKDFKAW DSHQDLSVAP PPPSRRTLPS SLSQNLNAET
     VKAVPRLLKS LLPGGKEGRD QTAVHQQSLP RIVVQSASVE EDMSKQQQAV PIDETEIPRS
     VPLPPPIIPE TEDSTASPVS EASSGYMSTS ISTVTLSEVY TLSWDLPSSY GSRDGFEMVL
     DEHEEENVVT QKFSPFSDTT QSDTLILDQS GPQKLLSLKQ KADAECLDQE PSKPDVTPSQ
     QEPNQFLSDQ LKEAEKSDPA AEAELPDQTE QKQDHGSEQR DHSETHKDSE VARKNGTNQT
     EVRHVDHSEP KTASKEDLEV AATNKVECEL ALSNETQQSA QEGERRLEST VPQPQQPTQD
     QTASDFIQDP SPSLIQASGP DPGPPVDLGA QASSKQQSTS DVPETNGASF LPSSSATSEV
     QQPAASVKPA KGPISSPKSG PSVANPFKIQ KVKSSDLKSF LQILSEEEHD KPTLVDQHSS
     CGTGPNVSVP KENLEIISDT EDGDTAASAV LPEWLKEGEF VSVGANKSGT VRYLGPTDFA
     EGIWVGVELE VPAGKNDGSV AGKHYFHCNP GYGVLVRPDR VTRGGAKRHR QQQQQQQKRR
     SANLSGSSPN LAALTALAKG EGGTGSTSRS RGENRKSWNT
//
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