ID I3J0M4_ORENI Unreviewed; 331 AA.
AC I3J0M4;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Phospholipid phosphatase 3 {ECO:0000313|Ensembl:ENSONIP00000002414.1};
GN Name=LOC100698562 {ECO:0000313|Ensembl:ENSONIP00000002414.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000002414.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000002414.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PA-phosphatase related phosphoesterase
CC family. {ECO:0000256|ARBA:ARBA00008816}.
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DR RefSeq; XP_003442019.2; XM_003441971.4.
DR AlphaFoldDB; I3J0M4; -.
DR STRING; 8128.ENSONIP00000002414; -.
DR Ensembl; ENSONIT00000002415.2; ENSONIP00000002414.1; ENSONIG00000001926.2.
DR GeneID; 100698562; -.
DR KEGG; onl:100698562; -.
DR CTD; 559124; -.
DR eggNOG; KOG3030; Eukaryota.
DR GeneTree; ENSGT00940000164486; -.
DR HOGENOM; CLU_021458_3_0_1; -.
DR InParanoid; I3J0M4; -.
DR OMA; FKPCTRP; -.
DR OrthoDB; 25293at2759; -.
DR TreeFam; TF316040; -.
DR Proteomes; UP000005207; Linkage group LG4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006644; P:phospholipid metabolic process; IEA:InterPro.
DR CDD; cd03384; PAP2_wunen; 1.
DR Gene3D; 1.20.144.10; Phosphatidic acid phosphatase type 2/haloperoxidase; 1.
DR InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR InterPro; IPR043216; PA_PP_rel.
DR PANTHER; PTHR10165; LIPID PHOSPHATE PHOSPHATASE; 1.
DR PANTHER; PTHR10165:SF94; PHOSPHATIDIC ACID PHOSPHATASE TYPE 2D; 1.
DR Pfam; PF01569; PAP2; 1.
DR SMART; SM00014; acidPPc; 1.
DR SUPFAM; SSF48317; Acid phosphatase/Vanadium-dependent haloperoxidase; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 58..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 154..298
FT /note="Phosphatidic acid phosphatase type 2/haloperoxidase"
FT /evidence="ECO:0000259|SMART:SM00014"
SQ SEQUENCE 331 AA; 36688 MW; 0AF396C4C6F5B52B CRC64;
MQKLNSTGTH GSMLPQDEEL QRRLADSGGS GEGKENGAGK QFLTQPEVES SFCTKRKMLV
CLDVLCLCIA SIPFFACEMK FVTPYKRGFF CGDPSITYPN ITTEAIPDSL LIAGGIAITG
VAIAVGECYR VRFRGVHSRA FVRNCYVSCL YKELGSFLFG CCVGQSLTNM AKLSVGRLRP
NFLDVCNITY ASINCKEGSY VPAESIVCSA QKKLEEEARK SFFSGHASFA MYTMLYLAFY
LQARLSWRGA RLLRPLIQFF LVMIAIYTGL SRISDYRHHP TDVLTGFIQG GLTAYWVAFY
ISPMFKPCAR PDRSPTSMSL ESPLSSQQTV C
//
