ID I3J2C7_ORENI Unreviewed; 993 AA.
AC I3J2C7;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Sterile alpha motif domain containing 11 {ECO:0000313|Ensembl:ENSONIP00000003017.2};
GN Name=SAMD11 {ECO:0000313|Ensembl:ENSONIP00000003017.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000003017.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000003017.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005478246.1; XM_005478189.3.
DR AlphaFoldDB; I3J2C7; -.
DR STRING; 8128.ENSONIP00000003017; -.
DR Ensembl; ENSONIT00000003018.2; ENSONIP00000003017.2; ENSONIG00000002412.2.
DR GeneID; 100706647; -.
DR KEGG; onl:100706647; -.
DR CTD; 148398; -.
DR eggNOG; KOG4333; Eukaryota.
DR GeneTree; ENSGT00940000160830; -.
DR HOGENOM; CLU_023292_0_0_1; -.
DR InParanoid; I3J2C7; -.
DR OMA; ISPYFHT; -.
DR OrthoDB; 2912923at2759; -.
DR TreeFam; TF331299; -.
DR Proteomes; UP000005207; Linkage group LG20.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd09579; SAM_Samd7_11; 1.
DR Gene3D; 3.10.390.10; SAND domain-like; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR010919; SAND-like_dom_sf.
DR InterPro; IPR000770; SAND_dom.
DR PANTHER; PTHR10417; GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN; 1.
DR PANTHER; PTHR10417:SF12; STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 11 ISOFORM X2; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF01342; SAND; 1.
DR SMART; SM00454; SAM; 1.
DR SMART; SM00258; SAND; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF63763; SAND domain-like; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS50864; SAND; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 161..247
FT /note="SAND"
FT /evidence="ECO:0000259|PROSITE:PS50864"
FT DOMAIN 845..891
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 43..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 338..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 469..505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 580..612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 646..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 923..993
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..317
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..399
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..498
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..671
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 672..747
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 755..774
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 942..981
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 993 AA; 108999 MW; 47D3073629838C91 CRC64;
MWEVGAVRLA ESAAAAASWK LLNGNLSGNF IRPLSLGDTG LRKTKRRVSK SGSAQLADEE
DAQVGSGEQQ LFTCYRRSAP TNMPAIKKER LDGDDMALTA FNPSEYLAPL NATAIPVVTP
HPPPYDHIFA HHRAYLGLHD SALHHQHLHH HTDDLMVERF SSIPDFQPFF DNGEPCIEVE
CGENKALLYI NKLCQGSKGP SIKYRGEWLT PNEFQFVSGR ETAKDWKRSI RHKGKSLKTL
MSKGILQVHP PICDCPGCRI SSPVNRGRLA EKRTIPLPPN RVPKKELASI FSSDDSEGSD
RASGDHAHIK QEDELHYSIM RKSRDTDLST IISNLHHTRQ HGMPEGQSAS DHGTSTGHTD
DLLGKRRSFS PNSSSECPSE SKKLRSVSPK ENSQSPGVEA GGSHGHMSPE EHYRRMMSAL
SEQGSYEEQQ QRLYQLASSM GLPGHDMLRA RQEALAAAVR NPVALEAHLP SAGSSSSSSQ
RRKQGLPQHR DAHYTDREMS HPPPLLSPPT APHIALGPHL RPPFLGMPSA LCQAPGYGFL
QPAQAELFAR QQELLRKQNL ARLEMSAELL RQKELENLHQ RQQQQRLLGS DPLGALPPGI
PPDHPALRSL HDIPEGHPLR EELARRTNAM LVLRHGATTP LLTLNHQQQQ PGAASTPKDT
QPQSSTAGTD AESRKMSRRV PQTQIRSGDH REGREDRGRE EDMEVHEEEM KDSDSETEMC
DERLERVGAK SSSKPKDRGK DTGSKGVCDT AKETVESSGR LSAPCSSAGT ESPSRHLFTP
GLGKTDLKYH LPPGFLPPLP ALHAQSFPFG FPYANPYFHT GSLGGLFMDG EDSATANPAE
DISKWSVEDV CGFISSLAGC AEYTQVFREQ AIDGETLPLL TEEHLLNTMG LKLGPALKIR
SQVARRVGRL FYMTGFPLAF PFPPSAALRP PERDRDPLTT PSDTPLPLSL SVPHRPTSTS
SSSSPYSGPT PGCSSPKQEN GNVVGRYEAK TPS
//
