ID I3J2S5_ORENI Unreviewed; 427 AA.
AC I3J2S5;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Septin {ECO:0000256|PIRNR:PIRNR006698};
GN Name=septin6 {ECO:0000313|Ensembl:ENSONIP00000003165.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000003165.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000003165.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. Septin GTPase family.
CC {ECO:0000256|PIRNR:PIRNR006698, ECO:0000256|RuleBase:RU004560}.
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DR RefSeq; XP_013126779.1; XM_013271325.2.
DR RefSeq; XP_013126780.1; XM_013271326.2.
DR Ensembl; ENSONIT00000003166.2; ENSONIP00000003165.2; ENSONIG00000002528.2.
DR Ensembl; ENSONIT00000084973.1; ENSONIP00000070055.1; ENSONIG00000002528.2.
DR GeneID; 100691719; -.
DR CTD; 23157; -.
DR eggNOG; KOG3859; Eukaryota.
DR GeneTree; ENSGT00940000158026; -.
DR OrthoDB; 5396944at2759; -.
DR TreeFam; TF101080; -.
DR Proteomes; UP000005207; Linkage group LG2.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR CDD; cd01850; CDC_Septin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030379; G_SEPTIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016491; Septin.
DR PANTHER; PTHR18884; SEPTIN; 1.
DR PANTHER; PTHR18884:SF55; SEPTIN-6; 1.
DR Pfam; PF00735; Septin; 1.
DR PIRSF; PIRSF006698; Septin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51719; G_SEPTIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU004560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004560};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT DOMAIN 39..305
FT /note="Septin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51719"
FT REGION 408..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 321..399
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 427 AA; 48966 MW; 3CED08981C69E025 CRC64;
MASTEIARQA GEGARGVPLS GHVGFDSMPD QLVNKSVNHG FCFNILCVGE TGLGKSTLMD
TLFNTKFEGE PTQHNQPGVT LKSNTYELQE SNVRLKLTVV NTVGFGDQIN KEDSYKSIVE
FIDAQFEAYL QEELKIKRTL HSYHDTRIHA CLYFIAPTGH SLKSLDLVTM KKLDSKVNII
PIIAKSDAIS KSELAKFKIK ITSELVSNGV QIYQFPTDDE SVAEINSTMN SHLPFAVVGS
TEEVKIGNKM VKARQYPWGT VQVENETHCD FVKLREMLIR VNMEDLREQT HTRHYELYRR
CKLEEMGFKD TDPDSKPFSL QETYEAKRNE FMGELQKKEE EMRQMFVQRV KEKEAELKEA
EKELHEKFDR LKKLHQDEKK KLEEKKKSLD DEVNTFKQKK TAAELLQNQA QQAGGSTTLK
RDKERKN
//
