ID I3J397_ORENI Unreviewed; 401 AA.
AC I3J397;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Metadherin a {ECO:0000313|Ensembl:ENSONIP00000003337.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000003337.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000003337.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; I3J397; -.
DR STRING; 8128.ENSONIP00000003337; -.
DR Ensembl; ENSONIT00000003338.2; ENSONIP00000003337.2; ENSONIG00000002665.2.
DR GeneTree; ENSGT00940000154181; -.
DR HOGENOM; CLU_034908_1_0_1; -.
DR InParanoid; I3J397; -.
DR OMA; TTDFQWD; -.
DR Proteomes; UP000005207; Linkage group LG22.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR GO; GO:0045766; P:positive regulation of angiogenesis; IEA:InterPro.
DR GO; GO:0043123; P:positive regulation of canonical NF-kappaB signal transduction; IEA:InterPro.
DR InterPro; IPR031402; LYRIC.
DR PANTHER; PTHR23251; LYSINE-RICH CEACAM1 CO-ISOLATED PROTEIN LYRIC PROTEIN; 1.
DR PANTHER; PTHR23251:SF0; PROTEIN LYRIC; 1.
DR Pfam; PF15686; LYRIC; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT REGION 42..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 265..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..58
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..106
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..161
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..326
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..401
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 401 AA; 43918 MW; 3A877E4E0C8EEF58 CRC64;
MFLICVFSPL QKSQSNGQPV TVAQEEVKVA EAVSKLPAQI KTEKKQEVQA PVQVKKNKKK
NKTDVKPVQL LSSNDGKEPD DGVWETKVSN REKRQQRRKE KGPEDSGGPG SVEASKTHVE
ATVPAAVNKR NRGNHESFHS RTTGKGDAAS EAVKDKVSSS WRKEPSVNGG GWNDMSLKIP
GQMSTMEGNK WSAISAATHY RAPPEPQPWA QESQATAWSG IDGRIKADLS PVSFSMLGLN
TTDPISNSVD LQWASRPKVD DEWSGFNGMA AADPSSDWNA PVEHWGNYEE PPVLVTPAPV
QKEQPVPNKV LEDERDTEDP SGGEAKSKKK RKKKKKTEEE TASDAQTVST AHVVNTIPKP
QELPALPSKK QNASISSSQK RSEQIAEPPK SSQKKKVRRE T
//
