ID I3J448_ORENI Unreviewed; 1068 AA.
AC I3J448;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A {ECO:0000313|Ensembl:ENSONIP00000003638.2};
GN Name=ANKRD28 {ECO:0000313|Ensembl:ENSONIP00000003638.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000003638.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000003638.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; I3J448; -.
DR Ensembl; ENSONIT00000003639.2; ENSONIP00000003638.2; ENSONIG00000002905.2.
DR GeneTree; ENSGT00950000182908; -.
DR HOGENOM; CLU_000134_58_1_1; -.
DR Proteomes; UP000005207; Linkage group LG11.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 11.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24178:SF45; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR Pfam; PF00023; Ank; 4.
DR Pfam; PF12796; Ank_2; 7.
DR Pfam; PF13637; Ank_4; 2.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 27.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR PROSITE; PS50297; ANK_REP_REGION; 20.
DR PROSITE; PS50088; ANK_REPEAT; 22.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 18..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 64..96
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 97..129
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 130..162
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 163..195
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 196..228
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 229..261
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 262..294
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 295..328
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 329..361
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 362..394
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 395..419
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 443..475
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 476..508
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 509..551
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 606..638
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 676..708
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 709..741
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 742..774
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 779..801
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 846..878
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 879..901
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 962..990
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 1068 AA; 115415 MW; 721677B1ED60839D CRC64;
MVLHVNKEKY QNRDNFDFFI YLFCAFFLFF LLQPPLLKAI FNVDPDEVRS LIFKKEDVNA
QDNEKRTPLH AAAYLGDAEI IELLILSGAR VNAKDNKWLT PLHRAVASCS EDAVQVLLKH
SADVNARDKN WQTPLHIAAA NKAVRCAEAL VPLLSNVNVS DRAGRTALHH AAFSGHLEMV
RLLLSRGANI NAFDKKDRRA IHWAAYMGHI EVVKLLASHG AEVACKDKKS YTPLHAAASS
GMISVVKYLL DLGVDINEPN AYGNTPLHVA CYNGQDVVVN ELIDCGANVN QVNEKGFAPL
HFTAASRHGA LCLELLVCNG ADVNIKSKDG KTPLHMTAIH GRFSRSQAII EKGAEIDCED
KNGNTPLHIA ARYGHELLIN TLISNRADTA KRGIHGMFPL HLAALSGFSD CCRKLLSSGE
QHSTLLMPCH SLQCFDIDTP DDFGRTCLHA AAAGGNLECL NLLLNTGADF NRKDSFGRTP
LHYAAANCNY QCLFALVGSG ASVNDLDERG CTPLHYAAAS DTDGNGLGLE ASMLCLEYLL
RNDANPGIRD NQGYNAVHYA SAYGHRLCLD DNFIMGGSTF QAYHGHHQAM EVLVQSLLDL
DVRNSQGRTP LDLAAFKGHV ECVDVLINQG ASILVKDYTL KRTPIHAAAT NGHSECLRLL
IGNADLQSAV DIQDGNGQTP LMLAVLSGHT DCVYSLLNKG ANVEAKDKWG RTALHRGAVT
GHEECVEALL QHSASFLVRD CKGRTPIHLA AACGHIGVLG GLLHAAQSVE TLPVLTDNQG
YTPLHWACYN GHDTCVEVLL EQEVFHKADG NSFSPLHCAV IHDNEGAAEM LIDTLGPAIV
NSKDSKNRTP LHAAAFTDHV ECLQLLLSHN AQVNSVDAVG KTPLMMAAEN GQTNAVEVLV
SSAKADLTLQ DAAKNTALHL ACSKVCSTIW WHCALNLHSV LLKLNINLLA STSKDLSCPL
RPLHVAARNG LTVVVQELLA KGASVLAVDE NGYTPALACA PNKDVADCLA LILATMMPVS
PCTPAPTLPF SAINHYTTSP SKSVTFDSLP VLRGEHNEEL NDSDSETY
//
