ID   I3J9D9_ORENI            Unreviewed;       851 AA.
AC   I3J9D9;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 2.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=Sarcolemma associated protein {ECO:0000313|Ensembl:ENSONIP00000005479.2};
GN   Name=slmap {ECO:0000313|Ensembl:ENSONIP00000005479.2};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000005479.2, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Broad Institute Genome Assembly Team;
RG   Broad Institute Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSONIP00000005479.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_019214725.1; XM_019359180.1.
DR   AlphaFoldDB; I3J9D9; -.
DR   STRING; 8128.ENSONIP00000077891; -.
DR   Ensembl; ENSONIT00000005483.2; ENSONIP00000005479.2; ENSONIG00000004347.2.
DR   GeneID; 100692085; -.
DR   CTD; 572011; -.
DR   eggNOG; KOG3872; Eukaryota.
DR   GeneTree; ENSGT00940000157660; -.
DR   HOGENOM; CLU_359254_0_0_1; -.
DR   OrthoDB; 5398803at2759; -.
DR   TreeFam; TF318787; -.
DR   Proteomes; UP000005207; Linkage group LG5.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd21911; CC1_SLMAP; 1.
DR   CDD; cd22679; FHA_SLMAP; 1.
DR   Gene3D; 1.10.287.1490; -; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   PANTHER; PTHR15715; CENTROSOMAL PROTEIN OF 170 KDA; 1.
DR   PANTHER; PTHR15715:SF26; COILED-COIL DOMAIN-CONTAINING PROTEIN 136; 1.
DR   Pfam; PF00498; FHA; 1.
DR   SMART; SM00240; FHA; 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        823..842
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          28..85
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
FT   REGION          448..499
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          172..199
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          265..394
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          547..592
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          636..817
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        463..490
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   851 AA;  97078 MW;  FC69A145F57DF50A CRC64;
     MPSALAIFAC RPNSHPFQER HVYLDEPVKI GRSVARCRPA QNNATFDCKV LSRNHALVWF
     DHKTGKFYLQ DTKSSNGTFI NSQRLSRGSE ESPPCEVLSG DIIQFGVDVT ENTRKVTHGC
     IVSTIKLFLP DGMEARRRSD VIQPPLPLPI DKVAANTPSM YSQELFQLSQ YLQEALHREQ
     MLEQKLATLQ RLLATTQEAS ESSWQALIDE DRLLSRLEVM GSQIQAYSKS QTEEGIRKEL
     LALQEDKHNY ETTAKESLRR VLQEKIEVVR KLSEVERTLS NTEDECTHLK EMSERSQEEL
     RELANKYNAA VNEIKELTDK IKAAEGRQEE LTQRGATEKR ELELRIEEME EKEQVLQARI
     EALQADNDFT NERLAALQVR LEQLQEKSIK ENNSLDNCHV NNSGGDSTRI QQLIECPPVK
     QLKETVSSSI HKLANFDEVM DAHLQNNQTA GDDILTSPDR LKGNQMDAKE SDMSDTLSPS
     KDRSSDDTSD GNMNDQELNE PQNRVALLKA ELHRAGLEPG DTEQVIHHLH RELLEAQELA
     NTGKQKCLEL QALLEEERRS NSQLTEESTK QIQFLQTQLG KLQADMEALR EQRESTICST
     REELYSAQEE ILVLRHAMEA ATAEREREIT VLQTDLVSVR SELEHWRNTA AKYEEEITRL
     QEAFTQQKQQ QTAASELQAE CTALHQRCTC LQQDCDGLRA ERKTLTEKLH RLEAELSSSR
     EQSLVLSSSL ESMEKREEVL QDKLGSLENQ HLQDASRLKS QLDQAQARTH TLQKEYEDTQ
     SQLSDLRQRY ERTEQEKLNI HQELEQCKSN LKLLQDKSSS SGWSPWMPVV AVMVAVTAAV
     LYPNLSKSSS T
//