ID I3JAQ7_ORENI Unreviewed; 685 AA.
AC I3JAQ7;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Negative regulator of reactive oxygen species {ECO:0000313|Ensembl:ENSONIP00000005947.1};
GN Name=LOC100705002 {ECO:0000313|Ensembl:ENSONIP00000005947.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000005947.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000005947.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_003456685.1; XM_003456637.4.
DR AlphaFoldDB; I3JAQ7; -.
DR STRING; 8128.ENSONIP00000005947; -.
DR Ensembl; ENSONIT00000005951.2; ENSONIP00000005947.1; ENSONIG00000004723.2.
DR GeneID; 100705002; -.
DR KEGG; onl:100705002; -.
DR CTD; 375387; -.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000157975; -.
DR HOGENOM; CLU_024194_0_0_1; -.
DR InParanoid; I3JAQ7; -.
DR OMA; DWAMVTC; -.
DR OrthoDB; 4169395at2759; -.
DR TreeFam; TF317167; -.
DR Proteomes; UP000005207; Linkage group LG9.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR026906; LRR_5.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR PANTHER; PTHR24373:SF293; TOLL-LIKE RECEPTOR 3; 1.
DR Pfam; PF13306; LRR_5; 1.
DR Pfam; PF13855; LRR_8; 3.
DR SMART; SM00369; LRR_TYP; 10.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS51450; LRR; 4.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..685
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003672764"
FT TRANSMEM 641..666
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 685 AA; 78335 MW; 3D4975A2BB461E37 CRC64;
MPVHRLTPIL LCLLHMWRTL TPVSSHPQHH RCQLIQQTAC CNNGQLTSVP EGLPENIEEL
QLNYNLFETL QNASLLRYPS LTALSLACNN LSKIESNSFQ DSKLLKSLNL ANNSLYNSYE
ETSLALRKLS GLIALDLSEN KLTDEMAALL LQNLTSLEYL NLSGNLLLRV DEASFRDLHQ
LKELDLQRNL IFEIDNAFDS SPKLQRLNLA FNYLPCLTDF HMIQLEVLNA SHNFIEWFIS
RQDLNDTFQL ETLDLSDNKL LFFPFLPSQS HLRYLYLSHN AIKFYEHLAD NDTFPNSTKT
VEFYNFNKDI NNVTAQLWDE NLHGDISSLE TLDLIGNSLE YFPKGFIQKM PTLSRLQMRT
NCLRTLNLTS EQFSGSLYEL DVSNNELNQI SADKATLTTL ANLTYFNLSL NGLKWVPMGL
FSSLQSIRSV DLSYNNIDIC LSEEAEISMH TNSTCMNWKN VMSLRQLYLK GCNLKVIPNT
AFAGLSLTHL ELSDNPGVTI HQSIQSLSKT LQHLGLGNTH IKDIDLSHFQ SLKSLNISKN
FLLHLPHSLQ NLNLKVLDLR DNRLSTIPSG QADALAPKLQ TIFLTGNQFN CCQTEWFRTF
EATKTIHMVE QSAITCKDLF LRTHRVENPQ SFLCFEDRES IFWYILLFVP VFLFFTGVSI
IVLLTIKPTL LQKSIKKKCR KPTSY
//
