ID I3JAY2_ORENI Unreviewed; 370 AA.
AC I3JAY2;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=P-type ATPase N-terminal domain-containing protein {ECO:0000259|Pfam:PF16209};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000006022.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000006022.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; I3JAY2; -.
DR Ensembl; ENSONIT00000006026.2; ENSONIP00000006022.2; ENSONIG00000004785.2.
DR eggNOG; KOG0206; Eukaryota.
DR GeneTree; ENSGT00940000160463; -.
DR HOGENOM; CLU_000846_3_2_1; -.
DR InParanoid; I3JAY2; -.
DR OMA; YEQFHHL; -.
DR TreeFam; TF300654; -.
DR Proteomes; UP000005207; Linkage group LG23.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR032631; P-type_ATPase_N.
DR PANTHER; PTHR24092:SF198; PHOSPHOLIPID-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR24092; PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE; 1.
DR Pfam; PF16209; PhoLip_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 79..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 49..102
FT /note="P-type ATPase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16209"
SQ SEQUENCE 370 AA; 42244 MW; BBDB2B45EC109877 CRC64;
MRRGLTEVLH SIHLHDNAPC RNFFVRANSR HYHKPKQKKS FLCFRWGRSA DNVVRSYKYT
PLTFLPLTLF EQFQRAANVY YLLIMVLQCV PAISSVPWYI TIIPLISILS LRGLKDLSND
MVRLHSKRVF SFSVVQFSSV LCLSFQMKKW KDVCVGDVLR IHKDQVFPAD LLLLCSSEPH
SLCYVETADI DGETNLKYRQ ALSATHDELT SNPSEEALSA FDGVVRCEEP NNRLYSFRGQ
LQWRGEGLLL DSEHILLRGT VLRNTAFAYG LAIYTGADTK ILRNSGKVKL KRTQMEKVFN
KVVMGVSGWR QADKPAQARN TSLNEELGQV GYLLSDKTGT LTQNRLLVRQ CCIAGEIYGN
NSSFFYRLLN
//
