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Database: UniProt
Entry: I3JCW4_ORENI
LinkDB: I3JCW4_ORENI
Original site: I3JCW4_ORENI 
ID   I3JCW4_ORENI            Unreviewed;       224 AA.
AC   I3JCW4;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   23-MAY-2018, entry version 33.
DE   SubName: Full=Toll-interleukin 1 receptor (TIR) domain containing adaptor protein {ECO:0000313|Ensembl:ENSONIP00000006704};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000006704, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Ensembl:ENSONIP00000006704}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2012) to UniProtKB.
RN   [2] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=25186727; DOI=10.1038/nature13726;
RA   Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA   Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J.,
RA   Johnson J., Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J.,
RA   Amemiya C., Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A.,
RA   Bloomquist R., Carleton K.L., Conte M.A., D'Cotta H., Eshel O.,
RA   Gaffney L., Galibert F., Gante H.F., Gnerre S., Greuter L., Guyon R.,
RA   Haddad N.S., Haerty W., Harris R.M., Hofmann H.A., Hourlier T.,
RA   Hulata G., Jaffe D.B., Lara M., Lee A.P., MacCallum I., Mwaiko S.,
RA   Nikaido M., Nishihara H., Ozouf-Costaz C., Penman D.J., Przybylski D.,
RA   Rakotomanga M., Renn S.C., Ribeiro F.J., Ron M., Salzburger W.,
RA   Sanchez-Pulido L., Santos M.E., Searle S., Sharpe T., Swofford R.,
RA   Tan F.J., Williams L., Young S., Yin S., Okada N., Kocher T.D.,
RA   Miska E.A., Lander E.S., Venkatesh B., Fernald R.D., Meyer A.,
RA   Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA   Di Palma F.;
RT   "The genomic substrate for adaptive radiation in African cichlid
RT   fish.";
RL   Nature 513:375-381(2014).
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DR   EMBL; AERX01007108; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 8128.ENSONIP00000006704; -.
DR   Ensembl; ENSONIT00000006709; ENSONIP00000006704; ENSONIG00000005330.
DR   eggNOG; ENOG410IVIY; Eukaryota.
DR   eggNOG; ENOG411205V; LUCA.
DR   GeneTree; ENSGT00510000048428; -.
DR   InParanoid; I3JCW4; -.
DR   OMA; DVCVCHS; -.
DR   OrthoDB; EOG091G0EQB; -.
DR   TreeFam; TF330734; -.
DR   Proteomes; UP000005207; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; -; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR017279; Tol-interleuk_rcpt_adapt_Tirap.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR22662; PTHR22662; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF52200; SSF52200; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005207};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT   DOMAIN       76    151       TIR. {ECO:0000259|PROSITE:PS50104}.
SQ   SEQUENCE   224 AA;  25462 MW;  5C55AECEA6CF2868 CRC64;
     MQGWFQKLLK SRGSLSKQHN KEATKGLVTS VSGVLTSSSS TLPSCSSSPL SSSPEGTPSK
     PQQLPTVLSS ELRWKRKYDI FVCHSSAQSD IEEATRLVSF LEDSTRSLRC FLWQRDACPG
     GAVCTEFCQA VENSHLRALL ITPNFVQDDW CNYMMHQVLT EGPMSNRMIP LLHSLSHSQY
     PKELKFYYYI DLSRNPVQAY TLVNRTVLQY LEDLVKKEMT HNFQ
//
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