ID I3JDT2_ORENI Unreviewed; 218 AA.
AC I3JDT2;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Sodium channel subunit beta-2 {ECO:0000313|Ensembl:ENSONIP00000007022.2};
GN Name=LOC100698560 {ECO:0000313|Ensembl:ENSONIP00000007022.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000007022.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000007022.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005474564.1; XM_005474507.3.
DR AlphaFoldDB; I3JDT2; -.
DR STRING; 8128.ENSONIP00000007022; -.
DR Ensembl; ENSONIT00000007027.2; ENSONIP00000007022.2; ENSONIG00000005584.2.
DR GeneID; 100698560; -.
DR KEGG; onl:100698560; -.
DR CTD; 6327; -.
DR eggNOG; ENOG502R29H; Eukaryota.
DR GeneTree; ENSGT01030000234556; -.
DR HOGENOM; CLU_090350_0_0_1; -.
DR InParanoid; I3JDT2; -.
DR OMA; RLACTFN; -.
DR OrthoDB; 5311693at2759; -.
DR TreeFam; TF331728; -.
DR Proteomes; UP000005207; Linkage group LG14.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR000920; Myelin_P0-rel.
DR PANTHER; PTHR13869; MYELIN P0 RELATED; 1.
DR PANTHER; PTHR13869:SF3; SODIUM CHANNEL SUBUNIT BETA-2; 1.
DR Pfam; PF07686; V-set; 1.
DR PRINTS; PR00213; MYELINP0.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..218
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025334963"
FT TRANSMEM 160..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..150
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 195..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 218 AA; 24211 MW; B582E1BA05973230 CRC64;
MSYPAQERRS GVQLVSALLL MLSLSGCSSM DVIVASSINA LNGTTVKISC VFTSCYKMDV
TKFAMNWTYQ ETRNDTHELF MTYYKKRGMV PLRSERFGER VTFAGNLDKN DLSITLSNVQ
LEDEGIYNCY VRNPPDRIQG HGIIQLNVVT ELPPPRDSTI AVAIGASVGG ALALLILSMV
VVKCLRRHRK QELISEEKME EEGKLEAEGV AEEGTKQP
//
