ID   I3JDU0_ORENI            Unreviewed;       794 AA.
AC   I3JDU0;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 2.
DT   27-MAR-2024, entry version 65.
DE   SubName: Full=Liprin-beta-2 {ECO:0000313|Ensembl:ENSONIP00000007030.2};
GN   Name=PPFIBP2 {ECO:0000313|Ensembl:ENSONIP00000007030.2};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000007030.2, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Broad Institute Genome Assembly Team;
RG   Broad Institute Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSONIP00000007030.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the liprin family. Liprin-beta subfamily.
CC       {ECO:0000256|ARBA:ARBA00007547}.
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DR   AlphaFoldDB; I3JDU0; -.
DR   Ensembl; ENSONIT00000007035.2; ENSONIP00000007030.2; ENSONIG00000005589.2.
DR   eggNOG; KOG1899; Eukaryota.
DR   GeneTree; ENSGT01050000244951; -.
DR   OMA; REVTHIT; -.
DR   TreeFam; TF314207; -.
DR   Proteomes; UP000005207; Linkage group LG1.
DR   CDD; cd09563; SAM_liprin-beta1_2_repeat1; 1.
DR   CDD; cd09566; SAM_liprin-beta1_2_repeat2; 1.
DR   CDD; cd09569; SAM_liprin-beta1_2_repeat3; 1.
DR   Gene3D; 1.20.5.340; -; 1.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR   InterPro; IPR029515; Liprin.
DR   InterPro; IPR037617; Liprin-beta_SAM_rpt_1.
DR   InterPro; IPR037618; Liprin-beta_SAM_rpt_2.
DR   InterPro; IPR037619; Liprin-beta_SAM_rpt_3.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR   PANTHER; PTHR12587:SF18; LIPRIN-BETA-2; 1.
DR   Pfam; PF00536; SAM_1; 2.
DR   Pfam; PF07647; SAM_2; 1.
DR   SMART; SM00454; SAM; 3.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR   PROSITE; PS50105; SAM_DOMAIN; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          467..531
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50105"
FT   DOMAIN          544..602
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50105"
FT   REGION          235..404
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          419..455
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          764..794
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          25..94
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          126..181
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        235..367
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        368..384
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   794 AA;  88914 MW;  B38E7CA432AE88A5 CRC64;
     MEYDIDFYKH FAWLRKVNLH SNANSESYQE RLSRLEGDKE SLILQVSVLT DQVEAQGVKI
     SDLQSSLMEH QHKLNSTEEM LQQELLHRAS LENQKLSLMG EVSYLKLKLA DMEGKQGHGG
     ERQHKAEGLL KELRILKDKV EHLEDQKLQY EKKLKATKAE ISSLQQLLHS KNAEIESLHS
     QLLARPSLTT ESAERDQELQ RLRSGMKSLA AANDEKDRRI EELTLLLNQC RQFREVSSNT
     RQAPSAVHTL SNGRSLSSSS EEEEQVLMKN GDTSSAKSED VKSEASTNSS VSQQTSISSV
     QKDSDSRSEV QTLSSSMNDI TNGTAQKTGP SEMRSHTLPV NSSLSEQNGI GDSSSEIQSQ
     RSPAGSEDGD SSQRKPEKGD DSTSSDTSPV HSGQRAVGSP EYMKNNRSFK RLWGKLRRTQ
     SGGLPATDPD SGQFRRGGLR ATAGPRLTRT PESFDSARDM NIPFSQWTKE QVCGWLEDYG
     LGQYVSLSRQ WVENGQTLLS ATPQDFEKEM AMKNPLHRKK LQLALRAFTT KVIEKSSELD
     HIWVTRWLDD IGLPQYKDQF HEARIDGRMI QYLTVNDLLT LKVTSQLHHL SIKCAIHVLH
     ANKFNPNCLR RRPVEEKHPP PSEVVQWSNH CVMEWLRAVD LAEYAPNLRG SGVHGGLIIL
     EPRFSSETLA LLLNIPPQKT LLRRHLATAF SALVGLQAMQ EKREYGNATG HVPLTTTAKV
     KPKKLGFTQF SHLRKRKPDE SADYICPIDS GALTVNGVSR LASSAQRGLS PRLDRQAEGE
     EQVGIKAQTN GPKQ
//