ID I3JQZ1_ORENI Unreviewed; 855 AA.
AC I3JQZ1;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=NACHT, LRR and PYD domains-containing protein 14 {ECO:0000313|Ensembl:ENSONIP00000011285.2};
GN Name=LOC102080519 {ECO:0000313|Ensembl:ENSONIP00000011285.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000011285.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000011285.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; I3JQZ1; -.
DR STRING; 8128.ENSONIP00000064218; -.
DR Ensembl; ENSONIT00000011294.2; ENSONIP00000011285.2; ENSONIG00000008974.2.
DR GeneTree; ENSGT01100000263529; -.
DR HOGENOM; CLU_002274_3_0_1; -.
DR Proteomes; UP000005207; Linkage group LG6.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd00116; LRR_RI; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR Pfam; PF13516; LRR_6; 5.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR SMART; SM00367; LRR_CC; 5.
DR SMART; SM00368; LRR_RI; 9.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT DOMAIN 80..212
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
SQ SEQUENCE 855 AA; 96061 MW; FAF4648A69845A76 CRC64;
MDLQTCLKAA LRSKYESLVE AFSKSSILPS RLCYQDVRYN YIEPDFFQHE YRSLDRSFFF
PDAPLADVLS CKCQHKNRNR TVITLGVSGV GKTTMVQSCA LDWAKDKGYH NISFLFPLTF
WELNLLKDRL SLIELLQTFY PELKELDASV LNEDGVWFIL DGLDEFQIQL NFGCPAVSDV
SEASTVDSFV TNLIRGNLLP RAHIWVTSRI SAESRIPPFY LLKKTELRGF SDEQKEQHFR
MVIGDSDLAN KAINHVKISR SLDSLCQIPP ICTIMASALK DHVKGQKGFK MHPLSLTEIY
NLGFGALEAK HLPIFTKLKK VALLRMGVRN VMYEDDLSGN GISVEEALAF AETCPLVLRT
ETGLNGTTVF RFGHLSVQEF LAASQKLEDI KTHKINLSSY IQDLVDKVLA NNKGVSDLLL
RFMFGLIKEH MLLLPNDLLF GYVKEKILSK ISSYSTVILF HCLREYDSQA LQEEVRFFQR
YGNSQIPGFS LMHWRELMQR IRAFEGIRET FEMEVLKFSN LTDKSCPALA AVLSSKESFL
RELDLGYNSF STSGVQELAE GLNSLNCRLK ILRLQGCGLT AETCQYLSQC LIQHKLQELD
LSSNGIGDQG LKLLSCGLGS SSCRLQTLKL YYCDLTVLSC ESIGEALKCE TSTLLELNLS
NNSLKDAGFK IICEGMYAWC SLQKLNVSRC GITAAGCRYL AKVLCSISQL TNDLDLSMNH
IGDKGVKEIS PGLMNPLSHL KTLNSLLPFS LSYCSLTDSC CAELASGLMS KVNILSELDL
SHNNLQDKGV KKLCIGLQSL QCKLEKLPGV PHPWCKVKQF CSSTNKSFCL EILHSSFINL
YFLFSQMIFF VSLCL
//
