ID I3JSC3_ORENI Unreviewed; 529 AA.
AC I3JSC3;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein {ECO:0000256|ARBA:ARBA00022414};
GN Name=zgpat {ECO:0000313|Ensembl:ENSONIP00000011768.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000011768.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000011768.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_003449142.1; XM_003449094.4.
DR RefSeq; XP_019205694.1; XM_019350149.1.
DR AlphaFoldDB; I3JSC3; -.
DR STRING; 8128.ENSONIP00000011768; -.
DR Ensembl; ENSONIT00000011777.2; ENSONIP00000011768.1; ENSONIG00000009365.2.
DR GeneID; 100689941; -.
DR KEGG; onl:100689941; -.
DR CTD; 84619; -.
DR eggNOG; KOG2185; Eukaryota.
DR GeneTree; ENSGT00390000000732; -.
DR HOGENOM; CLU_040504_1_0_1; -.
DR InParanoid; I3JSC3; -.
DR OMA; QYTRGIG; -.
DR OrthoDB; 3060898at2759; -.
DR TreeFam; TF105970; -.
DR Proteomes; UP000005207; Linkage group LG20.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd20384; Tudor_ZGPAT; 1.
DR Gene3D; 2.30.30.1190; -; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR041367; Znf-CCCH_4.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR46297; ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46297:SF1; ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF18044; zf-CCCH_4; 1.
DR SMART; SM00443; G_patch; 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00723}.
FT DOMAIN 184..211
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 329..375
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT ZN_FING 184..211
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 98..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 378..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 510..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 457..509
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 104..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..136
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..529
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 529 AA; 58007 MW; EC337D5DA3332D09 CRC64;
MDEESLEAAI AAYGAQLQQV ETALSAGLDP TQHSDLLKLK EDLCQLIELT EASLVSVRKS
QLLASLEESS GLQVNASEAA TDANGGLDAE FAAFYSELGE SSGNSSDSKE RTKEGEGGEV
DYEEEEEEEE EDKEEEDALS GTKVRAPYRT TWGTLEYHNA MVVGAEPPDG DEAQVRVLYI
YPTQKSMKPC PFYLEDKCRF QDNCRFSHGE VVYVSELREF LDSDLSNLEE GSSCLARHED
GIWHPGKIQE IDSGFYTVKF DSLLLKDAVV EADGVIPPLR EDDPLSSESD SDDIGDGDDA
MGYAKVIDSA VEPTETSSSA NFGGWEAHTR GIGSKLMLKM GYEYGKGLGK LQEGRVEPVM
AVVLPKGKSL DQCAEFTQRR TQSKAAKDGA QTGRPKRRRK PRVATRGGQT VFDFLNCKLG
GKTAHPPEGG AVAPSAATGV EAYRGGKSTK RSLNVRLFQA AERVSQTERE IQKLSESLSR
QAGRDPSIVK QLEEKLSAAR RLLVQQKAQE LSIQREHKKA DTHKKMTEF
//
