ID   I3JSX6_ORENI            Unreviewed;      1556 AA.
AC   I3JSX6;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 2.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=RB1 inducible coiled-coil 1 {ECO:0000313|Ensembl:ENSONIP00000011971.2};
GN   Name=RB1CC1 {ECO:0000313|Ensembl:ENSONIP00000011971.2};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000011971.2, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Broad Institute Genome Assembly Team;
RG   Broad Institute Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSONIP00000011971.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   Ensembl; ENSONIT00000011980.2; ENSONIP00000011971.2; ENSONIG00000009527.2.
DR   eggNOG; KOG4572; Eukaryota.
DR   GeneTree; ENSGT00390000015871; -.
DR   HOGENOM; CLU_003711_0_0_1; -.
DR   Proteomes; UP000005207; Linkage group LG18.
DR   GO; GO:0000045; P:autophagosome assembly; IEA:InterPro.
DR   CDD; cd17060; Ubl_RB1CC1; 1.
DR   InterPro; IPR040040; ATG11.
DR   InterPro; IPR019460; Atg11_C.
DR   InterPro; IPR045326; ATG17-like_dom.
DR   PANTHER; PTHR13222; RB1-INDUCIBLE COILED-COIL; 1.
DR   PANTHER; PTHR13222:SF1; RB1-INDUCIBLE COILED-COIL PROTEIN 1; 1.
DR   Pfam; PF10377; ATG11; 1.
DR   Pfam; PF04108; ATG17_like; 1.
PE   4: Predicted;
KW   Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT   DOMAIN          121..536
FT                   /note="Autophagy protein ATG17-like"
FT                   /evidence="ECO:0000259|Pfam:PF04108"
FT   DOMAIN          1444..1550
FT                   /note="Autophagy-related protein 11 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10377"
FT   REGION          215..277
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          635..676
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          864..926
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          955..1056
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1108..1222
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1248..1323
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1372..1399
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        219..239
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        240..277
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1556 AA;  178240 MW;  CC797749E6A8262E CRC64;
     MKLYVFQVNN GSTLTFDTDL AVQTVQELKH AIQAKYKIAI PHQVLVVNGG ECMAAERRVC
     SYSAGTETNP IFLFNKEMIL SDRDPTIPKT TFSIESEIQV KVEESLLMPA VFHTVASRTQ
     LALEMFEVAN KLCSFCERLV HDEHLQHQGW AAIMANLDDC TLSYQKLLIK FNTAYTNYQH
     DLEEIKVKLT KLGTAVSVMA KIPLLECLTR QSYRESMEKS SSTPEKDSDE TEEEKSTDSV
     LCTTEAQMHS KSSASFSASG TATCEPAEDQ ESNEMTDSGG LRAALLDDDT PELTNPSVFN
     VTLLDWINVQ DRPNDVESVV RKCFDSINRL DPRIIQPFLT ECHDTISKLD NQNMKSIKGL
     EDRLYALDQM LASCKKLVNE QKELAQGFLA NQKRAENLKD TSVLPDLCMS HTNQLMIMLN
     NHRKLLEIKK KCTTAKQELA NNLQVRLKWC CYVMLHADQD AEKLQALFRL LTELMERVRV
     VEALSTVPQM YCLAVVEVVR RKMFMRHYRE WANALVKDGK QLYEAEKFKR ESFGKLFRKS
     FLRNRLFRGL DSWPPTSFCT RRPRRFDDEL PDISLEDLQY LKSCCPVEVQ PFLMLPTVCN
     FEPLNHHIET LHQLVQAAQS VDEMSQTITD LLSEQRASYS QSAHRSTTLS PQSEMPATTT
     PVSPKTPSSL SLQGPSCQPL HVPVPAPLED LSPDSIDAQT FDFETIGHPN MDPVLQQGSL
     DLDSLAESPE SDFMSAVNEF VIEENLTSPN PISDPTSPEM MVESLYSSVI NAIDNKRMQD
     TTILERENSK IAVLQQVIER YRIAAEESHS SLRNVKDDLC HLRGLVLKEQ HDFGFVLRSM
     STEVHNIVDS ICQTHEQALK EQHQSELLAI RQDFEKEVKT LTEENQVNQS IVRDVQRAML
     ELEGLMERKE KELTQLENER ERWIQTDGIQ TDKITNLEQI VSDQVEENKK LAASRDSLST
     QLENLHFEIE RSQQKIRQEL EVVAQNNLKE LEDRMKHEHK AEMETLTKDN QEALENLAVE
     NSAKLSKAAD HHATAIKEKD SQVKDLEARI AELAELRCKL EVELALKESE TEDLKRLFEE
     SRIQQEEDVK SQIEAKTKVL GEELAVVKKE LQLKNEEYEV DLAELRTLMR IEKDHCISEL
     VDRHEEETIL LRNKLSSLQQ QAQEAGRNHA EQHRKLKEEL DQQLAAVCEE KEKQLNSFQE
     REQELRTVIS SLQQENDLLS QKVEQDRLAF EKHLEKEKAT EAAAPDAFKE LEHEKEEMEK
     RLLGKIRQLE NELHEVRSSK SFHSFLSPLS LDSALQERLQ QERASLQAQM ELMEKKKNEE
     IQNMKTSLIA EQQTNFNTVL TREKMKKEQI ISDLTEKLHK VTQQQEKDKA LIEKLSEDRA
     SVMQEKKHLE EELNRLRSTA LVSSAFFNPN PSAQDPFAET DRLASVAAIR DDEHVDSAVE
     ASMVTMSQSM SSVSSRHSDK IAIRDFQVGD LVLIILDERH DNYVLFTVGP TLYFLHSESL
     TALDLKPASG TSRRPWVLGK VMEKEYCQAK KAQNRFKVPL GTKFYRVKAV PWNRKV
//