ID   I3JT30_ORENI            Unreviewed;       605 AA.
AC   I3JT30;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   SubName: Full=Kelch like family member 14 {ECO:0000313|Ensembl:ENSONIP00000012025.1};
GN   Name=KLHL14 {ECO:0000313|Ensembl:ENSONIP00000012025.1};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000012025.1, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Broad Institute Genome Assembly Team;
RG   Broad Institute Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSONIP00000012025.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_005476456.1; XM_005476399.3.
DR   RefSeq; XP_013126367.1; XM_013270913.1.
DR   RefSeq; XP_013126369.1; XM_013270915.1.
DR   RefSeq; XP_019203953.1; XM_019348408.1.
DR   RefSeq; XP_019203954.1; XM_019348409.1.
DR   AlphaFoldDB; I3JT30; -.
DR   STRING; 8128.ENSONIP00000012025; -.
DR   Ensembl; ENSONIT00000012034.2; ENSONIP00000012025.1; ENSONIG00000009568.2.
DR   GeneID; 100701876; -.
DR   KEGG; onl:100701876; -.
DR   CTD; 57565; -.
DR   eggNOG; KOG4441; Eukaryota.
DR   GeneTree; ENSGT00940000159556; -.
DR   HOGENOM; CLU_004253_14_3_1; -.
DR   InParanoid; I3JT30; -.
DR   OMA; RETRMQH; -.
DR   OrthoDB; 5472491at2759; -.
DR   TreeFam; TF328485; -.
DR   Proteomes; UP000005207; Linkage group LG18.
DR   CDD; cd18453; BACK_KLHL14; 1.
DR   CDD; cd18243; BTB_POZ_KLHL14_printor; 1.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR047027; KLHL14_BACK.
DR   InterPro; IPR030584; KLHL14_BTB_POZ.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR45632:SF6; KELCH-LIKE PROTEIN 14; 1.
DR   PANTHER; PTHR45632; LD33804P; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 2.
DR   Pfam; PF01344; Kelch_1; 3.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 2.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 6.
DR   SUPFAM; SSF117281; Kelch motif; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          33..128
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
FT   REGION          72..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   605 AA;  68050 MW;  60AB7C3BBF61ED13 CRC64;
     MSRSGDRTST FDPTHSDTLL HGLNLLWRKQ LFCDVTLTAQ GQQFHCHKAV LASCSQYFRS
     LFSSHNVINN EGSKGDQGSS GTPSSSPDDK LVTTSARPIN NLVLQGCSSI GLRLVLEYLY
     TANVTLSLDT VEEVLSVSKI LNIPQITKLS VQFLNDQISV QNYKQICKIA ALHGLDETKK
     LANKYLVEDV LLLNFEEMCA MLDALPPPVE SELALFQMSV LWLEHDRETR MHYAPDLMKR
     LRFALIPAPE LVERVQSVDF MRSDPVCQKL LLDAMNYHLM PFRQHCRQTM ASRIRSNKRM
     LLLVGGLPPG PDRLPSNLVQ YYDDEKKTWK ILTIMPYNSA HHCVVEVENF LLLLGGEDQW
     NPNGKHSTNF VSRYDPRFNS WIQLPPMQER RASFFACRLD KHLYVIGGRN EAGYLSSVES
     YNLETNEWNY VSSLPQPLAA HAGAVHNGKI YISGGVHNGE YVSWLYCYDP IMDVWARKQD
     MNTKRAIHAL AGMNDRLYAI GGNHLKGFSH LDVMLVECYD PKADQWNILQ TPILEGRSGP
     GCAVLDDSIY LVGGYSWSMG AYKSSTICYS PEKGTWTELE GEVAEPLAGP ACSTVILPAC
     LPFNK
//