ID I3JTT8_ORENI Unreviewed; 352 AA.
AC I3JTT8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=AKT1 substrate 1 {ECO:0000313|Ensembl:ENSONIP00000012283.1};
GN Name=akt1s1 {ECO:0000313|Ensembl:ENSONIP00000012283.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000012283.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000012283.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_003442571.1; XM_003442523.4.
DR AlphaFoldDB; I3JTT8; -.
DR STRING; 8128.ENSONIP00000012283; -.
DR Ensembl; ENSONIT00000012292.2; ENSONIP00000012283.1; ENSONIG00000009777.2.
DR GeneID; 100689736; -.
DR KEGG; onl:100689736; -.
DR CTD; 84335; -.
DR eggNOG; ENOG502RY6G; Eukaryota.
DR GeneTree; ENSGT00390000017397; -.
DR InParanoid; I3JTT8; -.
DR OMA; VPVWGCK; -.
DR OrthoDB; 4215423at2759; -.
DR Proteomes; UP000005207; Linkage group LG4.
DR GO; GO:0032007; P:negative regulation of TOR signaling; IEA:InterPro.
DR GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; IEA:InterPro.
DR InterPro; IPR026682; AKT1S1.
DR PANTHER; PTHR21844; AKT1 SUBSTRATE 1 PROTEIN; 1.
DR PANTHER; PTHR21844:SF2; PROLINE-RICH AKT1 SUBSTRATE 1; 1.
DR Pfam; PF15798; PRAS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT REGION 156..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 329..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..194
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..211
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 37607 MW; CB58C7789F3191D9 CRC64;
MASITQSSEL EIPDNHKESW LALLSAAEVY CQKSGCDLAI LTACKKFRST TGEGEVGRKR
ESGSAFPREC DFSYNVWGQG FLAESARRYM DDIGVLHSTT MLTAQKHTRQ AGGEGGTKLV
VDLTSDPGNR GSLTSDIVVG GVSPNGRLYS QSYPSIYSSG AVTGQGGGQN GTGEREREKS
ALEAERGLQR SGIEDLEEEV EDEEEEEDMD ERRPYGNESA GVFSMDEDSV SRDCEPFFES
DGEEESTDGS LSEDAPPPSR GMAVGQGAYS SRQSHPMALA RSLPVSVPVW GCRGSRAAQG
DSNSGERSGC ADLEHIAASM KALLAPGATD GTEMFGALPR PRLNTGDFSL KQ
//
