ID I3JVL1_ORENI Unreviewed; 356 AA.
AC I3JVL1;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=GRAM domain-containing protein 2B-like {ECO:0000313|Ensembl:ENSONIP00000012906.2};
GN Name=LOC102077765 {ECO:0000313|Ensembl:ENSONIP00000012906.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000012906.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000012906.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005476197.1; XM_005476140.3.
DR AlphaFoldDB; I3JVL1; -.
DR STRING; 8128.ENSONIP00000012906; -.
DR Ensembl; ENSONIT00000012916.2; ENSONIP00000012906.2; ENSONIG00000010263.2.
DR GeneID; 102077765; -.
DR eggNOG; KOG1032; Eukaryota.
DR GeneTree; ENSGT00940000165115; -.
DR HOGENOM; CLU_050698_2_0_1; -.
DR InParanoid; I3JVL1; -.
DR OMA; WSSHHRE; -.
DR OrthoDB; 45896at2759; -.
DR TreeFam; TF332065; -.
DR Proteomes; UP000005207; Linkage group LG18.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR46645:SF1; GRAM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46645; GRAM DOMAIN-CONTAINING PROTEIN 2B-RELATED; 1.
DR Pfam; PF02893; GRAM; 1.
DR SMART; SM00568; GRAM; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 307..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 112..179
FT /note="GRAM"
FT /evidence="ECO:0000259|SMART:SM00568"
SQ SEQUENCE 356 AA; 40378 MW; 7DE780C7CE235187 CRC64;
MTLCVREPEL FMFHHDSEKQ EILTGQLCLD HQSDICIPVS WDSTVEGGEI FGTRRSSVRS
SKKKNKQSTS LDAVQLEGQL NQSLDSNMAL REQTIAEENL QRSDDQYFKH NKSFHKLFPE
IPVWDSLAHA FMCSLQKEVL YHGKLFVSQN HVCFYSSVLL KDTKVVIPVS SIKDVKKHGS
ALSILSIQTA EEKYSFVSLR NREKCYKLLQ SVCSHVQAEA VNSSPHLSVA ENEADHNPQF
SSFSSLDDRV DFLSSDSLDT SFLQTSSEGP STTNSTRQNS IIDEEDSAGL WIWRFITRLP
EIKTLSVVFH IYMVLLVLLL LVSGYIGLRI LALQEQLNSL GALTDWSSHH REYQET
//
