ID I3JXY4_ORENI Unreviewed; 1335 AA.
AC I3JXY4;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Hemicentin 2 {ECO:0000313|Ensembl:ENSONIP00000013729.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000013729.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000013729.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSONIT00000013739.2; ENSONIP00000013729.2; ENSONIG00000010911.2.
DR eggNOG; KOG4475; Eukaryota.
DR GeneTree; ENSGT00940000154614; -.
DR HOGENOM; CLU_000087_0_0_1; -.
DR InParanoid; I3JXY4; -.
DR OMA; WNNQGES; -.
DR Proteomes; UP000005207; Linkage group LG12.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 11.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR10075; BASIGIN RELATED; 1.
DR PANTHER; PTHR10075:SF63; CONTACTIN-4; 1.
DR Pfam; PF07679; I-set; 5.
DR Pfam; PF13927; Ig_3; 4.
DR SMART; SM00409; IG; 10.
DR SMART; SM00408; IGc2; 11.
DR SMART; SM00406; IGv; 5.
DR SUPFAM; SSF48726; Immunoglobulin; 10.
DR PROSITE; PS50835; IG_LIKE; 11.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1335
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025602642"
FT DOMAIN 375..462
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 465..547
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 556..632
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 637..721
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 728..804
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 811..891
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 900..983
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1005..1073
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1082..1161
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1179..1251
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1256..1335
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 1335 AA; 143836 MW; 7F6FBEB561573CB7 CRC64;
MAGALLKCLV LALSVSAHRL LADPRVETGD ESDDSASTLA FVFDVTGSMY DDLKQVIEGA
SRILEKTLSR RTRPIKNFVL VPFHDPGTFS PITQVSSDFK RKYFLALLQR ERVFVLTGDC
GDRSQPGYRA YEEIAATSSG QIFHLDKQQV NEVLKWVEET VQAMKVHLLS SNHDSAQENN
WEVPFDPSLR EVTVSLSGPA PEIQLSDPLG RVVGVEQGLK ELLNIPNSAR VINLKFPRPG
AWKLKISCSG RHTLRVTGVS SLDFRAGFSS VPVTEFNHTR ERPIKGLPSH VLLKCTGLKP
PGHLSHVELM SGSGRSLRTI PVPLPSDLGK QGLWSLPEFR TPSQSFFIRV TGKDEEGYRF
QRLSSVSYTN IIPDPPAVSM PTVVKGVYMQ PAVIGCSVKS DIPYRLRFTR SGITLGEERF
FQYSAVASWE IPKASAEDEG PYECMAQSSA GQGWAVTQLT VRDPPPVLKP PVNVTSSVGG
VAVLSCQVEG NMRHNLTWHR GGHAIRARAG RVKLLPNSFL QISEVRAQDA GEYRCVATNA
YGDSRIAVWL HVPEAPSVVV HPQSLAFSRG DEIRLVCSAS GSPPPRLFWS QGNVLNQHGV
LTIKGALPED AGNYTCLASN EAGTASQSVS LSYAEAPRIT VVQQVVLVTA GGDATLECQA
TGFPSPLVHW FKGELEVGSA PFVEQDIHRG TLHIRGVQEV DAGQYSCVAS SSAGTSSGTV
SLVVGAGPLF SEAPADVTAN VGENITLPCT ARGFPQPTVT WRRQDGRQIL MRTDSHSVWL
DDEGLYICEA KNQFGTIKSE ARVSVTGLEP PLLAHVAPVI TTGSGQSLSI PCMLLDGIPL
PERHWSKNGK PLNRRMFLRS DGSLYIERAI PEDTGIYVCT AVNVAGSANI TVSLEVHVPP
EISAGPYHYI ANEGVAIRLS CEATGVPKPD VVWSKVTLAT FGFSPSDSEG HLHIPNPSAE
DAGIYICTAT SPVGYASREI QLSVNSKANG GKQFAFGIVK EVPVGAEVVL PCEAEGSPSP
LVTWSRNGHP IPPVTAGFTV LPSGSLRITD VRLIDSKLYT CTAENPAGNT SLSYNLHIQA
KPRIQPAPSL LKALLGQTVT LPCVAQGEPS PEISWFRNGS PVGVKNVTPL RIQQVSLADQ
GAYRCVASNS AGQETLEIKL EILGECHEFN SSDLLKVANS KVIIPCPAKG SPNPKVRWFK
NGLEIHPEQP DFSVARDGAL VISAASASHS GDFKCVAVNE AGSVERKTRL KVNVPPEIQD
NGQPLNLTVT LKQPLTLGCD AFGIPSPTIT WTKDGKAVSV TEIGCSESTE FSLNMQDSLP
AQLKTQQERP KDNIT
//
