ID I3K2U9_ORENI Unreviewed; 400 AA.
AC I3K2U9;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Si:dkey-33c12.3 {ECO:0000313|Ensembl:ENSONIP00000015444.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000015444.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000015444.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR AlphaFoldDB; I3K2U9; -.
DR Ensembl; ENSONIT00000015457.2; ENSONIP00000015444.2; ENSONIG00000012264.2.
DR eggNOG; ENOG502QWG5; Eukaryota.
DR GeneTree; ENSGT00940000165724; -.
DR HOGENOM; CLU_012560_7_4_1; -.
DR InParanoid; I3K2U9; -.
DR OMA; IRLAYPS; -.
DR TreeFam; TF330122; -.
DR Proteomes; UP000005207; Linkage group LG19.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF4; SI:DKEY-33C12.3; 1.
DR Pfam; PF00038; Filament; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT DOMAIN 78..388
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 27..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 96..186
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 300..366
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 400 AA; 46060 MW; B3CBE68A662987F5 CRC64;
MSYDSFFSTR RPWDSYKGSR TITKSSVSSS FYPSSRAPPS GKRILRTSSS SLPDGSQRMN
LAQASSLNTE LLGLRSQERA QLVDLNDRFA TYIEKVRHLE LQNRALLAEL DALRRRQNDP
SRLQALYEGE ARSLRAMIDS ENGEKMRMEA EKDYLRDVYE QMKERYEEEA RRRMDAEEAL
QRAKEEASRA VVYNCDAEAT VASLCDEMVF LKKVFAEEQA ELQAQLQVAN ISIDMEVSRP
DLSTALRDIR AQYERLAHKN MQAAEEWYQS KFASVAEMAS KNNEAVHAIR EETMEYRRLL
QSRSSEIEAL RNVIDSLNKQ LEDLEETQSK EVEKYQMRIS ELERNIAEAK QEMARYLREY
QDLLNVKMAL DIEIAAYRKL LEGGGDSSGV PFPSCSKLKT
//
