ID I3K3F6_ORENI Unreviewed; 460 AA.
AC I3K3F6;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Butyrophilin subfamily 3 member A2 {ECO:0000313|Ensembl:ENSONIP00000015651.2};
GN Name=LOC109198421 {ECO:0000313|Ensembl:ENSONIP00000015651.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000015651.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000015651.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; I3K3F6; -.
DR Ensembl; ENSONIT00000015665.2; ENSONIP00000015651.2; ENSONIG00000004488.2.
DR eggNOG; ENOG502QSRZ; Eukaryota.
DR GeneTree; ENSGT01050000244843; -.
DR HOGENOM; CLU_013137_8_0_1; -.
DR TreeFam; TF331083; -.
DR Proteomes; UP000005207; Linkage group LG3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR24100; BUTYROPHILIN; 1.
DR PANTHER; PTHR24100:SF145; BUTYROPHILIN SUBFAMILY 1 MEMBER A1; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 37..460
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025415462"
FT TRANSMEM 256..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 52..146
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 155..240
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 291..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 362..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 439..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 460 AA; 52770 MW; 7F2C46D75563D0EA CRC64;
MSLSVTSRMS PIKNKHLLVL HHVVVVLLFL TQSCGGQHQM IGPTKPVVAM IGDDIILPCH
LEPAVDVVDL TVDWSRNDLK PRSVYVRREG VELLTEQNPL YTGRTSLSVN KLQCGDVSLK
LSTVQLSDAG TYKCLVPKFN AETVVTLAVG SVSSPVIELT NVKNEMVLEC KSNGWYPEPQ
MLWVYSEEKL ISVDPTKNVR GSDGLYSVST KVTVEKGQSY SLTCKVQQKN ISQIKEAHIH
VSGDLFMVQS NTAVHITVNL AVCLITVGTA VILIWKCGQK KTKISIHDED ENELHQTEME
EKLQRESEEK KRLEDELQNK DEDLKHVRQT IEKLMEQKTF LKNQREKLIT LLQEDKTEMK
EAVKKKEPKT EREKKMQKRE DKKVNLEKRT EVHEELLKMT EKLMEETENI IIQMTEKKGK
IEKDKEQIIK HLREKEKEIG EIKKKLSEKQ VRNTEQQRTE
//
