ID I3K4T6_ORENI Unreviewed; 603 AA.
AC I3K4T6;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=MAM domain containing 2 {ECO:0000313|Ensembl:ENSONIP00000016131.2};
GN Name=MAMDC2 {ECO:0000313|Ensembl:ENSONIP00000016131.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000016131.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000016131.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; I3K4T6; -.
DR STRING; 8128.ENSONIP00000041232; -.
DR Ensembl; ENSONIT00000016146.2; ENSONIP00000016131.2; ENSONIG00000012816.2.
DR eggNOG; ENOG502QVDI; Eukaryota.
DR GeneTree; ENSGT00940000156117; -.
DR HOGENOM; CLU_015093_0_0_1; -.
DR TreeFam; TF330345; -.
DR Proteomes; UP000005207; Linkage group LG7.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR CDD; cd06263; MAM; 2.
DR Gene3D; 2.60.120.200; -; 4.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000998; MAM_dom.
DR PANTHER; PTHR23282; APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR; 1.
DR PANTHER; PTHR23282:SF101; RT07201P-RELATED; 1.
DR Pfam; PF00629; MAM; 4.
DR SMART; SM00137; MAM; 3.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 4.
DR PROSITE; PS00740; MAM_1; 2.
DR PROSITE; PS50060; MAM_2; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT DOMAIN 1..100
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 99..266
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 277..435
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 441..599
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT REGION 460..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 603 AA; 67652 MW; 73F71C39CBD064EF CRC64;
RKRGVLLSPR LDHGEWSCLR LVYQITESGS LEVLQRTEGN SFDRPLWSSR LPSDSWVVSS
MDLRNNTEPY RVVIEGKPGS SKGSSVAIFE IHISPGYCLE CDFEESHLCG YNNQWNANVN
WYVGGGEVQV LHNDMPNDHT YNNRSGHFMY VDSIYAKTFK EVAKLVSPMT QVPMSGCLSF
QYQRSEMGNL FSVFTRDQLG QYQELWRAGL ENQNDWTEIP GEWISVQVDL KAPYSVQVVF
EVAFNSPRGG RVALDDISFS SQFCTTDTEP TFDPSIANCD FESGFCLYTQ EQAEESPWRR
VSVKPNIFRN GDHTTGAGSF LLAHARLGPR FGYVSRLIGP TLAGNMKYCL TFYFSLRGFN
QTDQALAVYL LQANGSQEKI WTQAERSRGI WIAADATFQT SQPAKVVFVS TCRSFWDCGS
VALDDISMSL GECLLSSLLP GRCDFEAGMC GYTQDKKSDA ADWERRRGPT PTSYTGPRGD
HTTGPGYYLH LEASPMLPGQ NARLLSRPVR GTRGRHCISF FYHMYGSGTG QLNVHINKYG
KEELLWQRSG EQSIAWLKAQ VEYECHSQHQ IVFEAIRGSS IRSDIAIDDV VLEGGPCPGH
SLT
//
