ID I3K6A6_ORENI Unreviewed; 342 AA.
AC I3K6A6;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Maternal B9.10 protein {ECO:0000313|Ensembl:ENSONIP00000016651.2};
GN Name=LOC100690323 {ECO:0000313|Ensembl:ENSONIP00000016651.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000016651.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000016651.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BTG family. {ECO:0000256|ARBA:ARBA00007989}.
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DR RefSeq; XP_003453511.1; XM_003453463.4.
DR AlphaFoldDB; I3K6A6; -.
DR STRING; 8128.ENSONIP00000016651; -.
DR Ensembl; ENSONIT00000016666.2; ENSONIP00000016651.2; ENSONIG00000013242.2.
DR GeneID; 100690323; -.
DR KEGG; onl:100690323; -.
DR CTD; 54766; -.
DR eggNOG; KOG4006; Eukaryota.
DR GeneTree; ENSGT00950000182952; -.
DR HOGENOM; CLU_079660_3_0_1; -.
DR InParanoid; I3K6A6; -.
DR OMA; YLHRKTY; -.
DR OrthoDB; 11568at2759; -.
DR TreeFam; TF105272; -.
DR Proteomes; UP000005207; Linkage group LG10.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.90.640.90; Anti-proliferative protein, N-terminal domain; 1.
DR InterPro; IPR002087; Anti_prolifrtn.
DR InterPro; IPR033332; BTG.
DR InterPro; IPR036054; BTG-like_sf.
DR PANTHER; PTHR22978; B-CELL TRANSLOCATION GENE; 1.
DR PANTHER; PTHR22978:SF5; PROTEIN BTG4; 1.
DR Pfam; PF07742; BTG; 1.
DR PRINTS; PR00310; ANTIPRLFBTG1.
DR SMART; SM00099; btg1; 1.
DR SUPFAM; SSF160696; BTG domain-like; 1.
DR PROSITE; PS01203; BTG_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 165..184
FT /note="Anti-proliferative protein"
FT /evidence="ECO:0000259|PROSITE:PS01203"
FT REGION 212..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..253
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 342 AA; 38359 MW; 9084A5CAAC60B24E CRC64;
MWLYLCFCIF DEAALQSKLS SLLSFSSKYV CLNCLVFTLL WEFLFSVVLG SLHVFYLKRS
FLKKIQFEFA GLGKCVAMKE EIAAAVFFLA RLVKRYGCLD NDSRERFAAS LTSLLFENYK
NHWHPSTPAR GQAYRCLRMN SVRLQDPVLE QACERSGVRY EDLGLPQELT VWVDPGEVSC
RYGEHSSPFC VSAVDNCRRG DGELSRRIHE AVERASLDVP SGSSSDEDED GGGDNSMSTS
TSSSSLSTLC PPQIPPMNSE PKTIPTVSNP NSVYRFSEFS PGAPQTWLRE KRKGFPGDMF
PPHGAPAGAQ FSSQKGFRSY RATFTFTGPR VDKYHWVSKS RS
//
