ID I3K9N5_ORENI Unreviewed; 372 AA.
AC I3K9N5;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Tripartite motif containing 55 {ECO:0000313|Ensembl:ENSONIP00000017830.2};
GN Name=trim55 {ECO:0000313|Ensembl:ENSONIP00000017830.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000017830.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000017830.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_003443662.1; XM_003443614.4.
DR AlphaFoldDB; I3K9N5; -.
DR Ensembl; ENSONIT00000017845.2; ENSONIP00000017830.2; ENSONIG00000014185.2.
DR GeneID; 100696347; -.
DR KEGG; onl:100696347; -.
DR CTD; 664753; -.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000154004; -.
DR HOGENOM; CLU_013137_5_1_1; -.
DR InParanoid; I3K9N5; -.
DR OMA; CDIHEDE; -.
DR OrthoDB; 5383069at2759; -.
DR TreeFam; TF331669; -.
DR Proteomes; UP000005207; Linkage group LG9.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16760; RING-HC_MuRF2; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR017903; COS_domain.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF640; TRIPARTITE MOTIF-CONTAINING PROTEIN 55; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51262; COS; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 10..65
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 106..148
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 256..314
FT /note="COS"
FT /evidence="ECO:0000259|PROSITE:PS51262"
FT REGION 314..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 170..226
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 314..331
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 372 AA; 41438 MW; A7C59108ABA5AF56 CRC64;
MDNLEKQLIC PICLEMFTKP VVILPCQHNL CRKCANDVFQ ASNPYLPTRS GSLTSGGRFR
CPSCRHEVIL DRHGVYGLQR NLLVENIIDM FKQESSSSKP APEKKEETPM CDIHEDEKIN
IYCVTHGVPT CSMCKVFGAH KDCEVAPLSS IYQTKKTELS DGIAMVVGNN DRMQGIISQL
EEACRAIEEN SRRQKTLVCE KFDHLYSILE EKKRELNQKV TDEQEEKVNY IRGLTSKYGD
HLEESCKILE MGIQAMDEPE MALFLQNTKP LLKKIEEASS AAHLDKVELG YESMDHYKVD
FKKEGKALRS IDFIQDDEDE DEEDEDAGAG AEEGEGSQTV SGGAVSATSA QPSAPPQQMS
SSPSAPTSTP ST
//
