ID   I3KCT7_ORENI            Unreviewed;       202 AA.
AC   I3KCT7;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 2.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Troponin I, skeletal, slow c {ECO:0000313|Ensembl:ENSONIP00000018932.2};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000018932.2, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Broad Institute Genome Assembly Team;
RG   Broad Institute Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSONIP00000018932.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Troponin I is the inhibitory subunit of troponin, the thin
CC       filament regulatory complex which confers calcium-sensitivity to
CC       striated muscle actomyosin ATPase activity.
CC       {ECO:0000256|ARBA:ARBA00001988}.
CC   -!- SIMILARITY: Belongs to the troponin I family.
CC       {ECO:0000256|ARBA:ARBA00009930}.
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DR   AlphaFoldDB; I3KCT7; -.
DR   Ensembl; ENSONIT00000018949.2; ENSONIP00000018932.2; ENSONIG00000015040.2.
DR   eggNOG; KOG3977; Eukaryota.
DR   GeneTree; ENSGT01030000234588; -.
DR   InParanoid; I3KCT7; -.
DR   OMA; NMEVGDW; -.
DR   TreeFam; TF313374; -.
DR   Proteomes; UP000005207; Linkage group LG7.
DR   GO; GO:0005861; C:troponin complex; IEA:InterPro.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.350; -; 1.
DR   Gene3D; 6.10.250.180; -; 1.
DR   InterPro; IPR001978; Troponin.
DR   InterPro; IPR038077; Troponin_sf.
DR   PANTHER; PTHR13738:SF38; NOVEL PROTEIN (ZGC:92233)-RELATED; 1.
DR   PANTHER; PTHR13738; TROPONIN I; 1.
DR   Pfam; PF00992; Troponin; 1.
DR   SUPFAM; SSF90250; Troponin coil-coiled subunits; 1.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207}.
SQ   SEQUENCE   202 AA;  23235 MW;  D7F5BECB8A13DD9E CRC64;
     NWATWHVKSS LICHILYYFQ PKCKISASRK LSLKILLLTR ATEDLEAEKA ANEEEKVRYL
     REKLPPLQLS GLNIDDLQKV CKEIHEKIHL VDEDRYDCEA KVLKNYRDIN ELQLKVQDLG
     GKFKKPALRK VRVSADEMLK ALFGSKTKGS MDLRANLKSV KKEDIKQEKE LTMEVGDWRK
     NVEAMSGMQG RKKMFDAAGG AQ
//