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Database: UniProt
Entry: I3KFR4_ORENI
LinkDB: I3KFR4_ORENI
Original site: I3KFR4_ORENI 
ID   I3KFR4_ORENI            Unreviewed;       886 AA.
AC   I3KFR4;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   18-SEP-2019, entry version 42.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSONIP00000019959};
GN   Name=LOC100694133 {ECO:0000313|Ensembl:ENSONIP00000019959};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000019959, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Ensembl:ENSONIP00000019959}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2012) to UniProtKB.
RN   [2] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=25186727; DOI=10.1038/nature13726;
RA   Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA   Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J.,
RA   Johnson J., Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J.,
RA   Amemiya C., Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A.,
RA   Bloomquist R., Carleton K.L., Conte M.A., D'Cotta H., Eshel O.,
RA   Gaffney L., Galibert F., Gante H.F., Gnerre S., Greuter L., Guyon R.,
RA   Haddad N.S., Haerty W., Harris R.M., Hofmann H.A., Hourlier T.,
RA   Hulata G., Jaffe D.B., Lara M., Lee A.P., MacCallum I., Mwaiko S.,
RA   Nikaido M., Nishihara H., Ozouf-Costaz C., Penman D.J., Przybylski D.,
RA   Rakotomanga M., Renn S.C.P., Ribeiro F.J., Ron M., Salzburger W.,
RA   Sanchez-Pulido L., Santos M.E., Searle S., Sharpe T., Swofford R.,
RA   Tan F.J., Williams L., Young S., Yin S., Okada N., Kocher T.D.,
RA   Miska E.A., Lander E.S., Venkatesh B., Fernald R.D., Meyer A.,
RA   Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA   Di Palma F.;
RT   "The genomic substrate for adaptive radiation in African cichlid
RT   fish.";
RL   Nature 513:375-381(2014).
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DR   EMBL; AERX01007285; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSONIT00000019976; ENSONIP00000019959; ENSONIG00000015852.
DR   GeneTree; ENSGT00970000193328; -.
DR   Proteomes; UP000005207; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR003879; Butyrophylin_SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRC_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR006574; PRY.
DR   InterPro; IPR003877; SPRY_dom.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 3.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF13765; PRY; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   PRINTS; PR01407; BUTYPHLNCDUF.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00589; PRY; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; SSF49899; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|SAAS:SAAS01046498};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005207};
KW   Leucine-rich repeat {ECO:0000256|SAAS:SAAS01143294};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS01046502};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW   Repeat {ECO:0000256|SAAS:SAAS01046485}.
FT   DOMAIN       81    213       NACHT. {ECO:0000259|PROSITE:PS50837}.
FT   DOMAIN      698    886       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
SQ   SEQUENCE   886 AA;  101016 MW;  E83DF2FE7FE6EF5A CRC64;
     KATLRRKFSH ILEGLATETN KISLNNIYTE LYVTEGGSGE VNKEHEVRQI ETTPRIHVGQ
     EKSIHCNHLF APLPERGCDI RTVVTRGVAG IGKTVLTNKF TLDWAEERAN KNLEFVFPLS
     FRELNLMKKK NFSLVELLVV LFPEIKDIEI FTNVKKNMLF ILDGLDESRL SLDFNKCEIL
     SDVTQTTTIA VLMTNLIRGR LLPMALVWIT SRPVASSQIP ANCVDLVTEV RGFNNLQKDE
     YFRRKISDEN LANRVIAHVK TCRSLHIMCH IPIFCWMAAT VFEKNMATKE SKDTPKTLTQ
     MYIHFLSLCE EAMKKRLTGR RESNADCVRA NLLALGKLAF QELEKGHLIF NESDLKLNGI
     DTEQASMFSG VYTQIFHEEM TVCKEKMFCF VHLSVQEFFA ALYVFLTFHN DNVNVLVKLS
     ASRRFLSRSS ELILYKEAVE KALRSEKGDF DMFLRFLLGL SLESNQTLLK HLMINNRTQQ
     KTRTEIVKHI KEKIRSSPSP DRCLNLFHCL NELNDHSLVE EIQSYLSSGS LNRANLSPAQ
     WATLVFVLLT SEEEQSVFEL GNYTRSEEGL LRLLPVVKTA QVAKLKSCNL TEHSSNDLAS
     FVSSASCLLK LLDLSDNEFH DLGVKRFSDG LRSSDCKLET LNLSLCGVGE EGCIFLASAL
     NSCHLRELDM SYNHPGNSGL NLLTALKEDP QCTLVKLSID QCGEFRIQPS PKKYTIKLTL
     DPNTAHKDLS LSEENRKATR WTKQPYPDHP ERFDYWTQVL CREGLKGRYY WETEWTGRVF
     IGVAYRRISR KGETDDCWLG RNNSSWGLNC NKDGYKALHK GTSIPITTKP NSNKVGVFLD
     WSAGTLSFYM LSCDSLKLLH TFHTTFDKPV YPGFHLAWVD SKVYLC
//
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