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Database: UniProt
Entry: I3KGN9_ORENI
LinkDB: I3KGN9_ORENI
Original site: I3KGN9_ORENI 
ID   I3KGN9_ORENI            Unreviewed;       772 AA.
AC   I3KGN9;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   23-MAY-2018, entry version 42.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSONIP00000020284};
GN   Name=LOC100695158 {ECO:0000313|Ensembl:ENSONIP00000020284};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000020284, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Ensembl:ENSONIP00000020284}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2012) to UniProtKB.
RN   [2] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=25186727; DOI=10.1038/nature13726;
RA   Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA   Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J.,
RA   Johnson J., Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J.,
RA   Amemiya C., Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A.,
RA   Bloomquist R., Carleton K.L., Conte M.A., D'Cotta H., Eshel O.,
RA   Gaffney L., Galibert F., Gante H.F., Gnerre S., Greuter L., Guyon R.,
RA   Haddad N.S., Haerty W., Harris R.M., Hofmann H.A., Hourlier T.,
RA   Hulata G., Jaffe D.B., Lara M., Lee A.P., MacCallum I., Mwaiko S.,
RA   Nikaido M., Nishihara H., Ozouf-Costaz C., Penman D.J., Przybylski D.,
RA   Rakotomanga M., Renn S.C., Ribeiro F.J., Ron M., Salzburger W.,
RA   Sanchez-Pulido L., Santos M.E., Searle S., Sharpe T., Swofford R.,
RA   Tan F.J., Williams L., Young S., Yin S., Okada N., Kocher T.D.,
RA   Miska E.A., Lander E.S., Venkatesh B., Fernald R.D., Meyer A.,
RA   Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA   Di Palma F.;
RT   "The genomic substrate for adaptive radiation in African cichlid
RT   fish.";
RL   Nature 513:375-381(2014).
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DR   EMBL; AERX01029440; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AERX01029441; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AERX01029442; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AERX01029443; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AERX01029444; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003452798.1; XM_003452750.4.
DR   Ensembl; ENSONIT00000020301; ENSONIP00000020284; ENSONIG00000016102.
DR   GeneID; 100695158; -.
DR   eggNOG; ENOG410INF7; Eukaryota.
DR   eggNOG; ENOG410XZT8; LUCA.
DR   GeneTree; ENSGT00530000063660; -.
DR   InParanoid; I3KGN9; -.
DR   OMA; YTYEPRA; -.
DR   OrthoDB; EOG091G038K; -.
DR   TreeFam; TF328550; -.
DR   Proteomes; UP000005207; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   Gene3D; 1.20.120.350; -; 1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR027359; Volt_channel_dom_sf.
DR   Pfam; PF00520; Ion_trans; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005207};
KW   Membrane {ECO:0000256|SAAS:SAAS00085096, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00084820,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00084701,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     66     85       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     91    111       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    132    151       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    193    216       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    228    248       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    260    286       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    413    431       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    443    459       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    471    492       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    532    554       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    637    664       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       70    291       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      411    663       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED      674    694       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   772 AA;  88601 MW;  CD5353ADF43FEDB4 CRC64;
     MSEPEKNENI PEASARKGIS NIGNTAKSKE DFNLAAIYVS DAQYNRNVYF DTLPQAVRLY
     MLYNHWALKV LLYFFMLVNL SLAIFEDPAV YPLPIWATML VEILCLLIFT IRLIHYAKVI
     LRDKFWKDPK NICIIVILTL TLVDMIIYGA LKAANYYGVR WSRVLRPLLL VNVTEGRQLR
     RAFRSIRNAL PQIFYVFMLF MFSILIFSLM ALKLLGKRGL TNINGTPYFT SYLEIMFDLY
     VLVTTANSPD VMMPAYNANF FFAVFFIVYI LINTYIFMSV FLAVVYNSYK KYLKEEVRQL
     VRAKRHKMVR AFGVLQEQRE EGGEPVVTQA SWNQLVRLVQ PNLSNAHREL LWSVSDDKNQ
     GAIGKVAFVQ LADLLNIEII TIKSRPHPLQ SLCPSLYQSA PSKLLCQLVQ HRAFVMVYDL
     IILVNAVFIG LDEENPMIAN SEWVFLALYI LEILLKLYVF EPRVFFSKHS FWNWFDTIIV
     ISALIATIIN SVMKSSSHFS SRQILDIVFI LRVLRLIRVV DSIKRFRIII NTLIRIGPAI
     LTFGQLIIVV YYIFAMVGME LFKGKVTFYE QSSTNLAKAY CGNPLLNGTD FAKLNYCKNN
     FNNVVSSFIL LVELTVVNQW HVLSSGFATV THISARIFFV LFHIIVVIVI LNIFVAFVLE
     AFFVEYSVDK SDLQTSLERK IEELELAVAQ ETMEDNLVNA METIDNDLGG SQSAKPNLPS
     LMFKIASKRY RTVDALLQRI FEADLDPEDF AENDDPETQG NENFANPLFS HA
//
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