ID   I3KH56_ORENI            Unreviewed;       794 AA.
AC   I3KH56;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=DnaJ homolog subfamily C member 10 {ECO:0000256|ARBA:ARBA00020920};
GN   Name=dnajc10 {ECO:0000313|Ensembl:ENSONIP00000020451.1};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000020451.1, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Ensembl:ENSONIP00000020451.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_013129477.1; XM_013274023.2.
DR   AlphaFoldDB; I3KH56; -.
DR   STRING; 8128.ENSONIP00000020451; -.
DR   Ensembl; ENSONIT00000020469.2; ENSONIP00000020451.1; ENSONIG00000016244.2.
DR   GeneID; 100711043; -.
DR   KEGG; onl:100711043; -.
DR   CTD; 54431; -.
DR   eggNOG; KOG0191; Eukaryota.
DR   eggNOG; KOG0713; Eukaryota.
DR   GeneTree; ENSGT00940000155558; -.
DR   HOGENOM; CLU_023279_0_0_1; -.
DR   OrthoDB; 52245at2759; -.
DR   TreeFam; TF105169; -.
DR   Proteomes; UP000005207; Unplaced.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR   CDD; cd06257; DnaJ; 1.
DR   CDD; cd03004; PDI_a_ERdj5_C; 3.
DR   CDD; cd03003; PDI_a_ERdj5_N; 1.
DR   CDD; cd02961; PDI_a_family; 1.
DR   Gene3D; 1.10.287.110; DnaJ domain; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 6.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR035674; ERdj5_TRX_C.
DR   InterPro; IPR035673; ERdj5_TRX_N.
DR   InterPro; IPR036869; J_dom_sf.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR017937; Thioredoxin_CS.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR44340; DNAJ HOMOLOG SUBFAMILY C MEMBER 10; 1.
DR   PANTHER; PTHR44340:SF1; DNAJ HOMOLOG SUBFAMILY C MEMBER 10; 1.
DR   Pfam; PF00226; DnaJ; 1.
DR   Pfam; PF00085; Thioredoxin; 4.
DR   PRINTS; PR00625; JDOMAIN.
DR   PRINTS; PR00421; THIOREDOXIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; Chaperone J-domain; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 6.
DR   PROSITE; PS50076; DNAJ_2; 1.
DR   PROSITE; PS00194; THIOREDOXIN_1; 2.
DR   PROSITE; PS51352; THIOREDOXIN_2; 3.
PE   4: Predicted;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..33
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           34..794
FT                   /note="DnaJ homolog subfamily C member 10"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003674676"
FT   DOMAIN          37..102
FT                   /note="J"
FT                   /evidence="ECO:0000259|PROSITE:PS50076"
FT   DOMAIN          122..236
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   DOMAIN          441..554
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   DOMAIN          657..784
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
SQ   SEQUENCE   794 AA;  90753 MW;  B07453F87A53A860 CRC64;
     MAHRVALRAQ RPRSVWLTVL PMLLTVLLVA VWAEGQDYYE LLGVSREATT KEIRRAFKQL
     ALTMHPDKNP GDASAHEKFL QVNRAYEVLK DEDLRKKYDK YGEKGLDEQQ GGRYESWNYY
     RYDFGIYDDD LEIITLDSGD FEAAVNSGEI WFINFYFPRC SHCHQLAPTW REFAKEMDGV
     IRIGAVNCGD NNHLCRRKGI NSYPSLYIYR SGQRPEKFNG ERNRDNLVRF SMQFITTTIT
     QLWQGNVFSE IESAFSSGLG WLITFCSDSG DCLEPRTRQK LAGMLDGLVK VGWMDCTTDE
     QICASFQVTS GATALFPPGS ALNKPGSVLW LNTLDSKEIY NQVINHLPDL ELLTSDSFQS
     KLAHHRWLIS FTFGNKNSAS NEYKKLQAFL RNDHIQVGRV DCIADSELCQ SLYIHKPCMA
     VFKGLGIHDF EIHHGKDVLY NIVGFARDSV RAFVTTLGPD NFPSDKKEPW LVDFFAPWCP
     PCRALLPELR KASIQLAGQM KFGTLDCTIH HNLCSRYNIQ AYPTTVIFNG SSVHEYEGHH
     SADGILEFIQ DLVNPSVLTL DPSSFTEKVK GRDEGQIWAV DFYAPWCGPC QALMPEWRRM
     ARLLSGQILV GSVDCQRFQS FCQSQSVRAY PEIRLYPGNS RQPDRYTSYN GWHRDAHSLR
     TWALSFLPRA SVDLTPETFR SLVLSGRDHW VLDFYAPWCG PCQHFAPEFE VLARMLKGEV
     RAGKVDCQAH YQTCQSAGIT AYPTVRFYPY LGKKRHEQSG EHINSRDANV IADTVRQRLQ
     QLLPRLHNKP KDEL
//