ID   I3KIB2_ORENI            Unreviewed;       416 AA.
AC   I3KIB2;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 2.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=SPRY domain-containing protein 3 {ECO:0000313|Ensembl:ENSONIP00000020857.2};
GN   Name=LOC100708393 {ECO:0000313|Ensembl:ENSONIP00000020857.2};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000020857.2, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Broad Institute Genome Assembly Team;
RG   Broad Institute Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSONIP00000020857.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; I3KIB2; -.
DR   STRING; 8128.ENSONIP00000038514; -.
DR   Ensembl; ENSONIT00000020876.2; ENSONIP00000020857.2; ENSONIG00000016562.2.
DR   eggNOG; KOG1477; Eukaryota.
DR   GeneTree; ENSGT00940000158675; -.
DR   HOGENOM; CLU_053348_0_0_1; -.
DR   TreeFam; TF331658; -.
DR   Proteomes; UP000005207; Linkage group LG20.
DR   CDD; cd12908; SPRYD3; 1.
DR   Gene3D; 2.60.120.920; -; 2.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR003877; SPRY_dom.
DR   InterPro; IPR035783; SPRYD3_SPRY.
DR   PANTHER; PTHR12864; RAN BINDING PROTEIN 9-RELATED; 1.
DR   PANTHER; PTHR12864:SF54; SPRY DOMAIN-CONTAINING PROTEIN 3; 1.
DR   Pfam; PF00622; SPRY; 2.
DR   SMART; SM00449; SPRY; 2.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR   PROSITE; PS50188; B302_SPRY; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT   DOMAIN          1..187
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
FT   REGION          348..370
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        348..362
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   416 AA;  46365 MW;  AE7822D61E79D747 CRC64;
     LNIFVLNKFF LFPKRTDLNI SSWIYLFINF QNRMAKEIKH YQGNSEEVGC YVAGRPLSKG
     NCYFEVTIVD TGVRGTIAVG LVPKFYRLDH QPGWLPYSVA YHADNGKLYN GNPVGQQFGP
     KCARGDRIGC GIHSENIEAG ITTVFFTKNG KEVGSVEVPV SAEGLFPAVG MHSMGEEVKV
     DLQAEWFLEE DDSMMMVDSH EDDWGRLYDV RVSGTLLEYV GKGKSIMDVG LAQARQPLTT
     RCHYYEVEIV DAGEKCYIAL GLARRDYPKN RHPGWSRGSV AYHADDGKIF HGSGVGDAFG
     PRCFKGDIMG CGIMFPRDYI LDGEGDTDDW DRLDIRPGHA SVQNVLYLND DEEEEEDGEE
     AGEQEQEGRK VTVFFTRNGK LMGRREMVIP PGGLYPTVGM LSSGEKVKVD LHPLSG
//