ID I3KJY6_ORENI Unreviewed; 565 AA.
AC I3KJY6;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Interleukin-1 receptor-like 1 {ECO:0000313|Ensembl:ENSONIP00000021431.1};
GN Name=LOC100702389 {ECO:0000313|Ensembl:ENSONIP00000021431.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000021431.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Ensembl:ENSONIP00000021431.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005475463.1; XM_005475406.3.
DR RefSeq; XP_019208894.1; XM_019353349.1.
DR STRING; 8128.ENSONIP00000048247; -.
DR Ensembl; ENSONIT00000021450.2; ENSONIP00000021431.1; ENSONIG00000016996.2.
DR Ensembl; ENSONIT00000046868.1; ENSONIP00000048247.1; ENSONIG00000016996.2.
DR GeneID; 100702389; -.
DR KEGG; onl:100702389; -.
DR eggNOG; ENOG502QWI7; Eukaryota.
DR GeneTree; ENSGT01090000259985; -.
DR HOGENOM; CLU_025552_3_1_1; -.
DR OMA; FKCFGEG; -.
DR OrthoDB; 4322253at2759; -.
DR TreeFam; TF325519; -.
DR Proteomes; UP000005207; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR015621; IL-1_rcpt_fam.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11890; INTERLEUKIN-1 RECEPTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11890:SF26; INTERLEUKIN-1 RECEPTOR TYPE 1; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR01537; INTRLKN1R1F.
DR SMART; SM00409; IG; 3.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..565
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041198281"
FT TRANSMEM 337..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 383..551
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 565 AA; 64026 MW; A7C9A155462F98F8 CRC64;
MDAFQLLFLV AVVTSISEWK SVSDSCNSQC KTMTEQSFRV LEGESFFLVP YTIFKPNFNN
KNFTWYKYIT QNQNISSDKK ARVHYQGEAL FLLNLSISDS AYYTAWEIKS SGRCVNYPVK
IEVYNASYKG SKMLSYGEIK NSDQSKKVEC PDPVQSACSE FKGNITWYKD YTLIKDQHEV
KVRVHHATKD HEGLYTCICT WAYNNKVYNT SGSRELVLQE TAMHHLEILT PADESREQFA
DEGSEIKLNC SVLCGANVKH DCNASWYING IPFKNRDGYS QTTKIAIAEP SKNTIVTAIL
TIKKVSAKDF QQKFGCFGEG YYKKKNTTLT LKRKESIIPL AIGGVCVLFI GVFVAVLVKY
FAIDLALFFR PYFPLSSSNK DTSLYDAYVV YQTPMDKITE DRLSQFIIQT LPSVLEDKCG
YRLFIHGRDD IPGEDRLELV EECMNQSRRL MVILTPDLGS GSVTTERWPA SPQTSVMGGF
DWQVGLHHAL VQRELSVILI QLGDTGPQQY THLPPGLQHL IRKSAPLKWP EGSGGAAAWN
SRFWKRVRYL MPATPVKKCA QSTIV
//
