ID I3KKA3_ORENI Unreviewed; 2339 AA.
AC I3KKA3;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 07-OCT-2020, entry version 45.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSONIP00000021548};
GN Name=cenpf {ECO:0000313|Ensembl:ENSONIP00000021548};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000021548, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000021548}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAY-2012) to UniProtKB.
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DR Ensembl; ENSONIT00000021567; ENSONIP00000021548; ENSONIG00000017088.
DR GeneTree; ENSGT00730000111187; -.
DR HOGENOM; CLU_000551_0_0_1; -.
DR InParanoid; I3KKA3; -.
DR OMA; YNAQLVQ; -.
DR Proteomes; UP000005207; Linkage group LG1.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 4.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT DOMAIN 6..259
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1380..1522
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 1618..1754
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2227..2271
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 72..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 400..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 500..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 876..896
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1808..1837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1925..1996
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2140..2236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 119..149
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 637..667
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 672..713
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 732..782
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 793..855
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 909..936
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 944..964
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 984..1011
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1038..1114
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1122..1156
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1164..1198
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1227..1254
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1286..1362
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1384..1481
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1503..1537
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1594..1663
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2077..2114
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 211..234
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..441
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..470
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..540
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1816..1837
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1925..1985
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2154..2174
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2175..2190
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2191..2210
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2339 AA; 269211 MW; 6BAFF78318BA8F53 CRC64;
MSLFLQVDSE RTETSALKRE NQSLVESCDS LEKARQKVVH DLGVKEQQVS YLEGQLNSCR
KTIERLEQEL KKHKNELDRS QPAGSSSLSS SSCELQTYAT PQKSFQTPAS IPAYRQHGIK
ILEELQEKYN QEVEERKRLE SELKVFQVKL LNQSSVSVSH KDIAARQAGS SIFPWQQQDS
AHCRQSQDIM ETPLKRRGTS LWDAHEETPI KPSQRMSSSR AAPSPSGSSQ QMEQLKTLNQ
ELRGRVSELE RNLANQEKEI RNQASKLQEL QTQLNQTRKD LSEQGRDLAK TKHELSQATD
RHQQIESKCS SLEQKLKQVT EEMSCQRHNA ESCRRALEQK LKDQERDSQK ELAQLQSSHH
ALDQQLNQTR TKLTQEIQQA KKDHNILQAD MEKMCFQKKQ MEKEMEEQKQ KLLRSEQSLQ
ACQTKEQDLR KKMEELQKEK NSMTVQLDQS NRRLSQLEEE KKSSDQSLKR TQGLLDDLKA
KSEGQVEELK KLQCKLEQQT QTSAREQENF KKTLSDAETR NDRSQNELQK QKQESERLSN
RVTVLEKESQ ELKSNFSASQ NECKELKREH QALLDWKNEK ETLINETEAV QKELTDKITS
LESSLGSLNE ANDELQKKLT CVEGEKASLS AHIDSLKGEL LNKCTDLEEK AHQYKELQSQ
FSEAGQKHAK DLENIGVQVA QLEAQVKDLE LRLQKEITRA ELAERMNTDL QDEHKATCDL
VSSKEQLVEL GRAEISQLRE SLAQTIAQQE EQNARWDQTE KINSLLEQIS SLEEKVDVNK
DAAEKLPVLK NELDVATQSN ADLKKSLEAL EKNHSSTIEM KSNLESTLAE KMNLISALEN
EVKDLTEKMG KESERHALEI ENFLKKEKSL DEQLEATKKS VSAAKAESSS RREEIRTMKA
TLSAASRGLE ERDNTIKGLK EKLNKAEAEQ TKTSELLKEK VVAMNKIKVQ LEMLQMDLED
NETAMTSFDS QVEQLKGTIE SLEVSVLEAR LDEVQSQNSL LESKYVTAKE ELFERTCEIT
RLEEEAIRRH ELEEKRSLNQ LLQEKNSLET SMKQLMNDKE QVESEMVHVN AEKKRLEVTV
DALSEENKQL QSNIERLTEE KQQTEAKINE ITARKHEAGS ALSQLTEAKA QVDDILKKTN
EENVQLAEKL HASTSEKNDL VTNLNQVVEE KVQLELSYNQ LSEENIKLQS SVNQITEKKL
QLQELIKGHG DEVASLREEN ECIQHSLLTS EQECQRLKEQ LELMEERTEE TNKEQYVYLA
VSALMFLRLN INIQIAFRHI CPSTESSLVN DELERYKEMI RKQENELETL RSEFDLLSSD
LELRKELTSE LEVQVQNLEK KLTQLSEEKE TLTLQLQTTK CQLTDVMEML EGLEMAKGGW
DEKFLQQESE LKRVRSEKAN LEQHILGMES ELETMQAEGA RLKDEMETQR RIFSGMEQKI
ETLITEVSKL RSELVSCTEE RDELSQSLSH WREKVHSLEK NNCDTRNLIS ILEDDIRAGR
KEYEALQSST DKLKTERQQL VEQVKELEQT ISQHCGEREE LIGHLNQIKE DHSSSSQNTE
SMAGKIKALE GEVIRLSQSL ESSLLEKGEI ASRLNSTQDE VQQMRTGIEK LQVRIESDER
KKKKMGELLK AAQRKSDSLQ DRIDSLEREK EDVEQSLEEA VLQVFSLTNI QKDNDCILLI
AKISELSTTL ENLRSEKEHM ERQLEIKNRE IEELKAAKEE LERGLEKAEA ERKEEEERQK
CRLEELEKEM KGEAERQIRV LDDLQAQLEA SRQREISLEQ KSTEEEAEKE RMQALLVQLE
EEKKHLLNSL QESQTEAERL RTHGEEWETE RNSLRTQTEA LEEEIEELKT LIKATEDKME
VLEKEKEEDR DQKQALERSV SSLIAEKEQI EGENGRFLQE KEELRTALLS LEQERDKLRS
SLLSVEEEKE RLDQERSALA SEREELQSSL SVLDKEKHDL QQKLSFLNQE KAREEEEKQK
IEAEKQELQS SVSLMEEEKK NLSSALLSLE QEKEKLAEEH EHLKTAVSSM EKELETHKLT
SRAARLTKDK DSALSKMSLW MKTCKQLEQE KEMMLNGSGL EETVKELEEM KTDLEEVNKL
LEEKSKEADE SMEKYCSLML EVHKLEKTNE ALKTRLELIG ASQNANDGHS SSTEGRQRSG
RKSSTRHQEL KIDDNTENMA PSSTQRSPPG SGKRGHREIS NRDGAQEALH NVTKRIKANA
MTTPKSRPEQ EDEEFRPEGL PELVQRGFAD IPLGEASPFI IRRTTVRRCS PRLAAKQTAS
DGKVSNAGIY LCFFTDAARC SVFATLAPNM STQCPAPLVP YKLLSRQVRS VKQQAIKRL
//
