ID I3KMC1_ORENI Unreviewed; 629 AA.
AC I3KMC1;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Clathrin interactor 1 {ECO:0000313|Ensembl:ENSONIP00000022266.1};
GN Name=LOC100707016 {ECO:0000313|Ensembl:ENSONIP00000022266.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000022266.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000022266.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005468038.1; XM_005467981.3.
DR AlphaFoldDB; I3KMC1; -.
DR STRING; 8128.ENSONIP00000022266; -.
DR Ensembl; ENSONIT00000022285.2; ENSONIP00000022266.1; ENSONIG00000017658.2.
DR GeneID; 100707016; -.
DR KEGG; onl:100707016; -.
DR CTD; 323870; -.
DR eggNOG; KOG2057; Eukaryota.
DR GeneTree; ENSGT00940000155650; -.
DR HOGENOM; CLU_032178_1_0_1; -.
DR InParanoid; I3KMC1; -.
DR OMA; HHTMEIK; -.
DR OrthoDB; 1532at2759; -.
DR TreeFam; TF313361; -.
DR Proteomes; UP000005207; Linkage group LG2.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR CDD; cd16989; ENTH_EpsinR; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR PANTHER; PTHR12276:SF45; ENTHOPROTIN-RELATED; 1.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT DOMAIN 16..149
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 218..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 347..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..258
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..275
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..364
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..392
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 68197 MW; CA067B461A87471F CRC64;
MLNMWKVREL VDKATNVVMN YSEVESKVRE ATNDDPWGPS GQLMSEISRA TFMYEQFPEV
MNMLWARMLR DNKKNWRRVY KSLLLLAHLI RNGSERVVTS AREHLYDLRS LESYHFVDEN
GKDQGVNVRQ KVKEMVEFVQ DDDRLREERK KAKKNKDKYV GVSSDSMGFR GYSGDRYDSG
DRKWDDDWEK KGPFPFSDKL GEISDKIGTT IDDTINKFRK KDRDDSPDRF SDNEEDRGRS
SHNGQQRKEF KDEEETVTTK SLQIVQATET TATRKRGGMP SKKVDLGAAA HYTGDKSPDT
TTKQMQPAAA PQPTNAALAD LLMVETTPSQ PAATDLIGGF ADFSSPAASA GLSSAAQPSS
PNGDFGEWNA FPGGQMPASA QTGNTSGNDL FAPMNAGPSV ATPTAAPTPA SGSGLASANL
FDLMGPTQTL TSSQSLSFSM SNTQSVSTTG LPQSKSQPLQ TMGGPLQPQP MQSMQPLQPV
QQGVSSQGAG AKASLPSTWS DHSVNISLDF LGPGMHPPKP AQPSLNTLQQ GNQAPGNMLS
QGFSNMSLGP TAVQPPVNPM MHPGAGMGMA PNQGMMGMRM WMHQGGMNMG MPQGGMTMGM
PGGMGMGMNP AMAQQPKQDA FADFGNFGK
//
