ID   I3KMM2_ORENI            Unreviewed;       223 AA.
AC   I3KMM2;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 2.
DT   27-MAR-2024, entry version 48.
DE   RecName: Full=palmitoyl-protein hydrolase {ECO:0000256|ARBA:ARBA00012423};
DE            EC=3.1.2.22 {ECO:0000256|ARBA:ARBA00012423};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000022367.2, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Broad Institute Genome Assembly Team;
RG   Broad Institute Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSONIP00000022367.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 2
CC       family. {ECO:0000256|ARBA:ARBA00006499}.
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DR   AlphaFoldDB; I3KMM2; -.
DR   Ensembl; ENSONIT00000022387.2; ENSONIP00000022367.2; ENSONIG00000017740.2.
DR   GeneTree; ENSGT00940000156197; -.
DR   Proteomes; UP000005207; Linkage group LG22.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR003140; PLipase/COase/thioEstase.
DR   PANTHER; PTHR10655:SF13; ACYL-PROTEIN THIOESTERASE 2; 1.
DR   PANTHER; PTHR10655; LYSOPHOSPHOLIPASE-RELATED; 1.
DR   Pfam; PF02230; Abhydrolase_2; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT   DOMAIN          13..217
FT                   /note="Phospholipase/carboxylesterase/thioesterase"
FT                   /evidence="ECO:0000259|Pfam:PF02230"
SQ   SEQUENCE   223 AA;  23990 MW;  62677E7004E43339 CRC64;
     MCGNNMSVPL LAEAVTVSGV EKETAAVIFL HGLGDSGHGW ADTLTGIRLP HVKFICPHAP
     PIPVTLNMKS MMPAWFDLMG LSPDSPEDES GIKKAAENIK AIIEHEARNG IPPNRIILGG
     FSQGGALSLY TALTCQHQLA GVVALSCWLP LHRSFPSASS GNKNLPILQC HGEMDAMIPV
     QFGAMTAEKL KSIVNPQMIT FKTFPGLPHS SCPQKLNPYF SFY
//